Results 141 to 150 of about 16,725 (189)

Peritoneal dialysis-induced senescence contributes to treatment failure in long-term PD. [PDF]

Sci Rep
Oberacker T, Kraft L, Pieper JM, Leibold T, Salega A, Schier R, Dong M, Balasubramanian A, Wülfrath HS, V Samson-Himmelstjerna FA, Thomsen SY, Schrumpf T, Kielstein JT, Eden G, Kolbrink B, Schulte K, Schmitt R, Latus J, Schanz M, Schricker S.   +19 more
europepmc   +1 more source

Cyclin-Dependent Kinases 4 and 6 Inhibitors: An Emerging Therapeutic Framework from Growth Suppression to Tumor Clearance. [PDF]

ACS Pharmacol Transl Sci
Ma C, Ji X, Huang W, Guo S, Wang L, Wu X, Zheng H, Wang J.   +7 more
europepmc   +1 more source

Prevalence of heterozygous and homozygous 9p21 deletions in human cancer: a tissue microarray study on 4,999 tumors from 125 different tumor types. [PDF]

Mol Med
Gorbokon N, Teljuk K, Schraps N, Lennartz M, Rico SD, Kind S, Reiswich V, Viehweger F, Lutz F, Fraune C, Luebke AM, Menz A, Schlichter R, Krech T, Hinsch A, Burandt E, Sauter G, Simon R, Steurer S, Marx AH, Lebok P, Dum D, Minner S, Jacobsen F, Clauditz TS, Hackert T, Uzunoglu FG, Bernreuther C, Kluth M.   +28 more
europepmc   +1 more source

Selected Potential Biomarkers in Laryngeal Cell Carcinomas. [PDF]

Cancers (Basel)
Paduch R, Klatka M, Klatka J.
europepmc   +1 more source

Expression of the cyclin-dependent kinase inhibitor p16 during the ongoing cell cycle [PDF]

FEBS Letters, 1995
It has been demonstrated that protein expression of p16, the inhibitor of cyclin‐dependent kinase 4 and 6, increases 4 fold at the G1/S transition when serum‐arrested cells are restimulated to logarithmic growth. We examined the cell cycle regulation of this cyclin‐dependent kinase inhibitor in cells separated according to their cell cycle phases by ...
T Soucek, O Pusch, M Hengstschläger
exaly   +3 more sources

Homozygous loss of the cyclin-dependent kinase 4-inhibitor (p16) gene in human leukemias [PDF]

Blood, 1994
Abstract Recently, it has been shown that the homozygous deletion of the cyclin- dependent kinase-4 inhibitor (CDK4I;p16) gene, which is mapped to chromosome 9p21, is frequently observed in a wide spectrum of human cancers, including leukemias. Therefore, the CDK4I gene is thought to be a putative tumor-suppressor gene.
Naoto Hirano, Kurokawa M, Yazaki Y
exaly   +5 more sources

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Familial uveal melanoma: absence of germline mutations involving the cyclin-dependent kinase-4 inhibitor gene (p16)

Ophthalmic Genetics, 1996
Kishore Wary, Arun Singh, Carol Shields   +2 more
exaly   +3 more sources

Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimerʼs disease

NeuroReport, 1996
Recent evidence indicates that an impairment of neuronal adaptive and reparative processes might be a key feature of the pathomechanism of Alzheimer's disease. Aberrations in the reparative neuronal response are likely to result from alterations of intracellular signal transduction cascades.
T, Arendt, L, Rödel, U, Gärtner, M, Holzer   +3 more
openaire   +2 more sources

Receptor-Ck regulates the expression of cyclin-dependent kinase inhibitors (p16; p27)

Molecular and Cellular Biochemistry, 1999
The present study was addressed to understand the interrelationship between Receptor-Ck induction-activation coupling; isoprenoids (derived from mevalonate pathway) and cyclin-dependent kinase inhibitors. The results reported here unambiguously reveal that isoprenoids regulate the expression of genes coding for CDK inhibited p16 and p27.
D, Kaul, M, Kaur
openaire   +2 more sources