Results 21 to 30 of about 79,986 (50)

Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation. [PDF]

Sci Rep, 2023
Ford K, Munson BP, Fong SH, Panwala R, Chu WK, Rainaldi J, Plongthongkum N, Arunachalam V, Kostrowicki J, Meluzzi D, Kreisberg JF, Jensen-Pergakes K, VanArsdale T, Paul T, Tamayo P, Zhang K, Bienkowska J, Mali P, Ideker T.   +18 more
europepmc   +1 more source

Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function. [PDF]

Sci Adv, 2023
Piol D, Tosatto L, Zuccaro E, Anderson EN, Falconieri A, Polanco MJ, Marchioretti C, Lia F, White J, Bregolin E, Minervini G, Parodi S, Salvatella X, Arrigoni G, Ballabio A, La Spada AR, Tosatto SCE, Sambataro F, Medina DL, Pandey UB, Basso M, Pennuto M.   +21 more
europepmc   +1 more source

Clinicopathological value of the upregulation of cyclin-dependent kinases regulatory subunit 2 in osteosarcoma. [PDF]

BMC Med Genomics, 2022
Mo C, Wu Y, Ma J, Xie L, Huang Y, Xu Y, Peng H, Chen Z, Zeng M, Mao R.   +9 more
europepmc   +1 more source

Long-lasting complete remission in a patient with systemic metastases of recurrent breast cancer treated with cyclin-dependent kinases 4/6 inhibitors: a case report. [PDF]

J Med Case Rep, 2023
Yoneto T, Hasumi K, Takahashi N, Seki N, Takeda Y, Yoshimoto T.   +5 more
europepmc   +1 more source

Cyclin-Dependent Kinases (CDK) and Their Role in Diseases Development-Review. [PDF]

Int J Mol Sci, 2021
Łukasik P, Załuski M, Gutowska I.
europepmc   +1 more source

Cyclin-dependent kinases as mediators of aberrant transcription in prostate cancer. [PDF]

Transl Oncol
Rahman R, Selth LA.
europepmc   +1 more source

Targeting CDK4 and CDK6 in cancer. [PDF]

Nat Rev Cancer, 2022
Goel S, Bergholz JS, Zhao JJ.
europepmc   +1 more source

Mechanistic Roles of Transcriptional Cyclin-Dependent Kinases in Oncogenesis: Implications for Cancer Therapy. [PDF]

Cancers (Basel)
Alrouji M, Alshammari MS, Anwar S, Venkatesan K, Shamsi A.   +4 more
europepmc   +1 more source

Circ_CEA promotes the interaction between the p53 and cyclin-dependent kinases 1 as a scaffold to inhibit the apoptosis of gastric cancer. [PDF]

Cell Death Dis, 2022
Yuan Y, Zhang X, Du K, Zhu X, Chang S, Chen Y, Xu Y, Sun J, Luo X, Deng S, Qin Y, Feng X, Wei Y, Fan X, Liu Z, Zheng B, Ashktorab H, Smoot D, Li S, Xie X, Jin Z, Peng Y.   +21 more
europepmc   +1 more source

Knockout of cyclin-dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice. [PDF]

Elife
Bruter AV, Varlamova EA, Stavskaya NI, Antysheva ZG, Manskikh VN, Tvorogova AV, Korshunova DS, Khamidullina AI, Utkina MV, Bogdanov VP, Baikova IP, Nikiforova AI, Albert EA, Maksimov DO, Li J, Chen M, Schools GP, Feoktistov AV, Shtil AA, Roninson IB, Mogila VA, Silaeva YY, Tatarskiy VV.   +22 more
europepmc   +1 more source