Results 91 to 100 of about 372,752 (258)
Neoplasia: An International Journal for Oncology Research, 2004 Barrett's esophagus (BE) epithelium is the precursor lesion for esophageal adenocarcinoma. Cell cycle proteins have been advocated as biomarkers to predict the malignant potential in BE.
Pierre Lao-Sirieix +4 more
doaj +1 more source
Live cell imaging of meiosis in Arabidopsis thaliana
eLife, 2019 To follow the dynamics of meiosis in the model plant Arabidopsis, we have established a live cell imaging setup to observe male meiocytes. Our method is based on the concomitant visualization of microtubules (MTs) and a meiotic cohesin subunit that ...
Maria A Prusicki +8 more
doaj +1 more source
Frontiers in Plant Science, 2014 Cyclin-dependent kinases, the master regulators of the eukaryotic cell cycle, are complexes comprised of a catalytic serine/threonine protein kinase and an essential regulatory cyclin.
Paolo eSabelli +4 more
doaj +1 more source
, 2009 We report here a novel role for Jun dimerization protein-2 (JDP2) as a regulator of the progression of normal cells through the cell cycle. To determine the role of JDP2 in vivo, we generated Jdp2 knock-out (Jdp2KO) mice by targeting exon 1 to disrupt ...
Yu-Chang Huang +9 more
core
Irreversible repression of DNA synthesis in Fanconi anemia cells is alleviated by the product of a novel cyclin-related gene [PDF]
, 1995 Primary fibroblasts from patients with the genetic disease Fanconi anemia, which are hypersensitive to cross-linking agents, were used to screen a cDNA library for sequences involved in their abnormal cellular response to a cross-linking challenge.
Digweed, M. +5 more
core
Cyclin-Dependent Kinase 5 and Insulin Secretion
, 2008 Cyclin-dependent kinase 5 (Cdk5) is emerging as a multifunctional kinase involved in regulating numerous cellular processes. Lately, Cdk5 has also emerged as a key controller of regulated membrane fusion in secretory cells.
Marko Jevsek +9 more
core +1 more source
Inhibition of Plk1 and Cyclin B1 expression results in panobinostat-induced G(2) delay and mitotic defects [PDF]
, 2013 Work by JP is funded by a Royal Society University Research Fellowship award. Experiments carried out by MBP were supported by the Department of Pathology, Albert Einstein College of Medicine / Montefiore Medical Center.The development of clinically ...
Parish, Joanna +9 more
core +1 more source
Cyclin-dependent kinase inhibitors in brain cancer: current state and future directions
, 2022 Cyclin-dependent kinases (CDKs) are important regulatory enzymes in the normal physiological processes that drive cell-cycle transitions and regulate transcription.
Viktorija Juric (7896287) +1 more
core +1 more source
Journal of Biological Chemistry, 1996 We have previously shown that the persistent activation of p42/p44MAPK is required to pass the G1 restriction point in fibroblasts (Pagès, G., Lenormand, P., L'Allemain, G., Chambard, J. C., Meloche, S., and Pouysségur, J. (1993) Proc. Natl. Acad. Sci. U.
J. Lavoie +4 more
semanticscholar +1 more source
, 2016 A new series of 2,6,9-trisubstituted purines, characterized by the presence of a common alkynyl substituent at C-2 and a range of different anilino/benzylamino groups at C-6, were synthesized.
Paul Tunnah (3024789) +8 more
core +1 more source