Results 171 to 180 of about 483,027 (406)
Quantitative Studies for Cell-Division Cycle Control
Frontiers in Physiology, 2019 The cell-division cycle (CDC) is driven by cyclin-dependent kinases (CDKs). Mathematical models based on molecular networks, as revealed by molecular and genetic studies, have reproduced the oscillatory behavior of CDK activity.
Yukinobu Arata, Hiroaki Takagi
doaj +1 more source
Proliferating cell nuclear antigen (PCNA)/cyclin in activated human T lymphocytes. [PDF]
, 1987 Pekka Kurki +3 more
openalex +1 more source
Minireview: Cyclin D1: normal and abnormal functions.
Endocrinology, 2004 Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle. Amplification or overexpression of cyclin D1 plays pivotal roles in
M. Fu +4 more
semanticscholar +1 more source
The Molecular Perspective: Cyclins
STEM CELLS, 2004 Abstract Learning Objective After completing this course, the reader will be able to: Describe the role of cyclins and cyclin-dependent kinases in cancer. Access and take the CME test online and receive 1 hour of AMA PRA category 1 credit at CME.TheOncologist.com
openaire +4 more sources
Advanced Science, Volume 12, Issue 22, June 12, 2025.This study reveals histone lactylation as a metabolic‐epigenetic regulator countering cellular senescence and skeletal muscle aging. Reduced lactylation impairs cell cycle, DNA repair and proteostasis pathways, while exercise restores glycolytic activity and lactylation levels, preserving muscle function.
Fanju Meng +16 more
wiley +1 more source
Coordinated synthesis of the nuclear protein cyclin and DNA in serum‐stimulated quiescent 3T3 cells [PDF]
, 1984 R Bravo
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Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species
Advanced Science, Volume 12, Issue 22, June 12, 2025.This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu +15 more
wiley +1 more source
Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2. [PDF]
, 1992 Helena E. Richardson +4 more
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Post‐Translational Modifications in Cilia and Ciliopathies
Advanced Science, EarlyView.This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley +1 more source
Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. [PDF]
, 1994 Dalia Resnitzky +3 more
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