Results 171 to 180 of about 241,661 (217)

Retraction Note: Cyclin D3 predicts disease-free survival in breast cancer. [PDF]

Cancer Cell Int
Chi Y, Huang S, Liu M, Guo L, Shen X, Wu J.   +5 more
europepmc   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Retraction: Maggot extract accelerates skin wound healing of diabetic rats via enhancing STAT3 signaling. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Correction: A novel synthetic melanin as a potential anticancer agent that induces apoptosis and cyclin D downregulation through distinct pathways. [PDF]

J Biol Chem
Kawamoto Y, Furuhashi Y, Ilmiyah SZ, Yamaguchi S, Nishimura N, Iwata R, Imoto A, Murate T, Ohmi Y, Permana S, Endharti AT, Ueno Y, Iida M, Yajima I, Ohgami N, Kato M, Takeda K.   +16 more
europepmc   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Ginsenosides in hepatocellular carcinoma: preclinical evidence, mechanisms, and clinical implications. [PDF]

Front Pharmacol
Yu C, Zhu X, Liu S, Ding Y, Fu H, Li Y, Gai M, Tan M, Zhao Z.   +8 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Transcriptional cyclin-dependent kinases as therapeutic targets in bone metastasizing cancers. [PDF]

Front Oncol
Kähkönen TE, Galabova G, Thormann M, Halleen JM.   +3 more
europepmc   +1 more source