Results 201 to 210 of about 403,677 (344)

Retraction: Cyclic AMP-response element regulated cell cycle arrests in cancer cells. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

Disrupting Cell Cycle Machinery: CREPT Is an Emerging Target in Cancer Therapy. [PDF]

Cancers (Basel)
Farooq U, Li J, Chang Z.
europepmc   +1 more source

D-type cyclin-dependent kinase activity in mammalian cells. [PDF]

, 1994
H Matsushime, Dawn E. Quelle, Sheila Shurtleff, Masatoshi Shibuya, Charles J. Sherr, Jun‐ya Kato   +5 more
openalex   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

SLC1A5-dependent glutamine uptake in hepatocytes promotes liver regeneration. [PDF]

Hepatol Commun
Duan Y, Peng S, Yue J, Ding F, Chen X, Pan W, Gao X, Pang P, Zhang Y, Wu W, Schneider KM, Cubero FJ, Trautwein C, Zhang L, Zhang Y, Liu J, Zhao G.   +16 more
europepmc   +1 more source

Chemically induced premature mitosis: differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation.

, 1991
Kathleen E. Steinmann, Glenn S. Belinsky, D Lee, Robert Schlegel   +3 more
openalex   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Cancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae, Megan Othus, Sandip Pravin Patel, Raid Aljumaily, Khine Z. Win, Tanya Pejovic, Sajeve S. Thomas, William R. Robinson III, Hye Sung Kim, Liam Il‐Young Chung, Christine M. McLeod, Helen X. Chen, Elad Sharon, Howard Streicher, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock   +16 more
wiley   +1 more source

miR-21-5p inhibitor enhances the radiosensitivity of human cervical cancer cells via blocking CPEB3-mediated CDK1/cyclin B pathway. [PDF]

Biochem Biophys Rep
Jiao L, Gao Y.
europepmc   +1 more source

Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2. [PDF]

, 1992
Helena E. Richardson, Daniel J. Lew, Martha Henze, Katsunori Sugimoto, Steven I. Reed   +4 more
openalex   +1 more source