Results 201 to 210 of about 230,940 (319)

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

Gut microbiota‐stem cell niche crosstalk: A new territory for maintaining intestinal homeostasis

iMeta, Volume 1, Issue 4, December 2022., 2022
Intestinal stem cells (ISCs) are protected by their niche and are regulated by Wnt, bone morphogenetic protein, and Notch. ISCs and their relationship with intestinal microbiota provide a feasible pathway to alleviate intestinal diseases. Diverse bacteria‐related postbiotics regulate ISCs and maintain their homeostasis.
Ning Ma, Xiyue Chen, Lee J. Johnston, Xi Ma   +3 more
wiley   +1 more source

Potential of Proliferative Markers in Pancreatic Cancer Management: A Systematic Review. [PDF]

Health Sci Rep
Salahi-Niri A, Zarand P, Mansouri N, Rastgou P, Yazdani O, Esbati R, Shojaeian F, Jahanbin B, Mohsenifar Z, Aghdaei HA, Ardalan FA, Safavi-Naini SAA.   +11 more
europepmc   +1 more source

Degradation of the proto-oncogene product p39mos is not necessary for cyclin proteolysis and exit from meiotic metaphase: requirement for a Ca(2+)-calmodulin dependent event.

, 1991
Thierry Lorca, Simon Galas, Didier Fesquet, Alain Devault, J C Cavadore, M. Dorée   +5 more
openalex   +1 more source

In vitro fusion of endocytic vesicles is inhibited by cyclin A-cdc2 kinase. [PDF]

, 1993
Philip Woodman, J P Adamczewski, Tim Hunt, W. G. Warren   +3 more
openalex   +1 more source

The Multiple Personalities of the Regulatory Subunit of Protein Kinase CK2: CK2 Dependent and CK2 Independent Roles Reveal a Secret Identity for CK2β

International Journal of Biological Sciences, 2005
Protein kinase CK2 (formerly casein kinase II), an enzyme that participates in a wide variety of cellular processes, has traditionally been classified as a stable tetrameric complex consisting of two catalytic CK2α or CK2α' subunits and two ...
doaj  

CHK1 inhibition overcomes gemcitabine resistance in non-small cell lung cancer cell A549. [PDF]

Mol Cell Oncol
Ke ZY, Fu T, Wang XC, Ma X, Yin HH, Wang WX, Liu YJ, Liang AL.   +7 more
europepmc   +1 more source

FLOT1 Is a Novel Serum Biomarker of Ovarian Cancer Targeted by N6‐methyladenosine Modification Inhibition

Cell Biology International, EarlyView.
ABSTRACT Ovarian cancer (OC) is a deadly disease and lacks a precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin‐1 (FLOT1) in OC tissue. To improve diagnostic sensitivity and accuracy, we evaluated the serum level of FLOT1 in OC patients and found that the serum concentration of FLOT1 as well as CA125 was
Bin Guan, Qi Lu, Junyu Chen, Jingyi Fang, Zhenyu Liu, Wei Li, Lingyun Zhang, Guoxiong Xu   +7 more
wiley   +1 more source

HU308 Mitigates Osteoarthritis by Stimulating Sox9‐Related Networks of Carbohydrate Metabolism

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 154-170, January 2023., 2023
ABSTRACT Osteoarthritis (OA) is characterized by progressive, irreversible erosion of articular cartilage accompanied by severe pain and immobility. This study aimed to assess the effect and mechanism of action of HU308, a selective cannabinoid receptor type 2 (CB2) agonist, in preventing OA‐related joint damage. To test the assumption that HU308 could
Idan Carmon, Lital Zecharyahu, Jinan. Elayyan, Sai R. K. Meka, Eli Reich, Leonid Kandel, Andras Bilkei‐Gorzo, Andreas Zimmer, Raphael Mechoulam, Nataly Kravchenko‐Balasha, Mona Dvir‐Ginzberg   +10 more
wiley   +1 more source

Distribution of Troy (Tnfrsf19) in the Gastric Gland During Postnatal Development: Effects of Early Weaning

Cell Biology International, EarlyView.
ABSTRACT This study investigates the distribution and role of the stem cell marker Troy (Tnfrsf19) in the gastric mucosa of rats during postnatal development and the effects of early weaning. Troy, previously identified as a reserve stem cell marker in adult gastric tissues, is examined across various developmental stages from birth to adulthood.
Isadora Campos Rattes, Kethleen Mesquita da Silva, Patrícia Gama   +2 more
wiley   +1 more source