Results 201 to 210 of about 22,958,501 (389)
Dynamic protein interactions probed by NMR spectroscopy
Abstract Dynamic protein–protein interactions are essential for diverse cellular processes but often evade structural characterization due to their transient, heterogeneous, and disordered nature. This review focuses on how nuclear magnetic resonance (NMR) spectroscopy can provide detailed, residue‐level insights into these complex interactions.
Jaeseok Lee, Jung Ho Lee
wiley +1 more source
β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression
Summary: Orderly progressions of events in the cell division cycle are necessary to ensure the replication of DNA and cell division. Checkpoint systems allow the accurate execution of each cell-cycle phase.
Ioanna Mavrommati+10 more
doaj
Activation of M-phase-specific histone H1 kinase by modification of the phosphorylation of its p34cdc2 and cyclin components. [PDF]
Pierre Pondaven+2 more
openalex +1 more source
Cyclins and cyclin-dependent kinases: a biochemical view [PDF]
openaire +3 more sources
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan+12 more
wiley +1 more source
Modeling the cell division cycle: cdc2 and cyclin interactions.
John J. Tyson
openalex +1 more source
Regulation of the microtubule nucleating activity of centrosomes in Xenopus egg extracts: role of cyclin A-associated protein kinase. [PDF]
Brigitte Buendia+2 more
openalex +1 more source
The history and future of targeting cyclin-dependent kinases in cancer therapy
U. Asghar+3 more
semanticscholar +1 more source
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang+7 more
wiley +1 more source