Results 201 to 210 of about 345,409 (245)
Small, EarlyView.Cancer cells are exposed to heightened levels of endoplasmic reticulum stress and inflammation within the tumor microenvironment which can lead to therapeutic resistance. To address this issue, liposome‐polymer nanoparticles loaded with copper diethyldithiocarbamate (CuET), a potent inhibitor of the p97‐UFD1‐NPL4 protein complex, and the anti ...
Radu A. Paun +4 more
wiley +1 more source
Impact of MiRNAs on Wnt-related gene activity in breast cancer. [PDF]
Sci RepSirek T +14 more
europepmc +1 more source
Small Methods, EarlyView.This review explores the dual roles of exosomes in gastrointestinal (GI) cancers as diagnostic biomarkers and therapeutic agents. It highlights advancements in exosomal miRNAs, lncRNAs, circRNAs, and proteins for cancer detection and prognosis. The study also examines engineering strategies for exosome‐based drug delivery systems, their potential to ...
Mohit J. Mehta +7 more
wiley +1 more source
CXXC5 is a ubiquitinated protein and is degraded by the ubiquitin-proteasome pathway. [PDF]
Protein SciAyten H +10 more
europepmc +1 more source
UroPrecision, EarlyView.Abstract Prostate cancer (PCa) is a multifaceted disease that envelops 1.41 million new cases globally. It is the second most common cancer reported in men. Its heterogeneity and indolent growth, coupled with incompetent early screening methods such as serum prostate‐specific antigen level estimations and digital rectal examinations, contribute to its ...
Anveshika Manoj +2 more
wiley +1 more source
Limocitrin induced cellular death through ERK pathways in human oral squamous cell cancer. [PDF]
Sci RepVelmurugan BK +6 more
europepmc +1 more source
VIEW, EarlyView.We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
wiley +1 more source
Nectin4‐targeted molecular imaging in solid tumors: Current status and future perspectives
VIEW, EarlyView.In this review, we provide a concise overview of the mechanisms by which Nectin4 contributes to the pathogenesis of various malignancies and detail the classes of Nectin4‐targeted molecular probes. We then delve into the significant advancements in Nectin4‐targeted molecular imaging techniques, encompassing both nuclear medicine and optical imaging ...
Yongshun Liu +6 more
wiley +1 more source
RBBP4 downregulation increases the sensitivity of A549 and HeLa cells to cisplatin by inhibiting cyclin D1 expression. [PDF]
Clinics (Sao Paulo)Zeng Z +6 more
europepmc +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.Abstract Objectives Sinonasal inverted papilloma (SNIP) is a benign tumor type that has been subject to growing levels of research interest owing to its potential for malignant transformation. However, there have been no studies to date of ferroptosis or related proteins in SNIP. Accordingly, this study was designed to examine correlative relationships
Dan‐Yang Li +7 more
wiley +1 more source