The receptor tyrosine kinase ErbB2/HER2 governs CDK4 inhibitor sensitivity, timing, and irreversibility of the G1/S transition. [PDF]
Nagasato-Ichikawa A +3 more
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CENPs in hepatocellular carcinoma: a comprehensive review of expression patterns, clinical correlations, and functional mechanisms. [PDF]
Zhou J +9 more
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The Elevation of <i>IRSp53</i> Expressing Level in Colon Cancer Specimens and the Secretome of hAMSCs' Therapeutic Impacts on Tumor Growth Promotion via Inhibiting of EGFR/c-Src/IRSp53/p-AKT/p-Stat3/cyclin D1 Signaling Cascade in HT-29 Colon Cancerous Cell Line. [PDF]
Alavi M +3 more
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Immunohistochemical Expression of p16, p53, BCL2, and Cyclin D1 in Gastrointestinal Stromal Tumors: Correlation With Clinicopathological Parameters. [PDF]
Zaki MM, Enan ET, Hany H.
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Regulatory interplay of cyclin D1 and INSM1 in suppressing INSL6 expression: Implications for breast cancer biology. [PDF]
Homma K +6 more
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Cyclins are regulatory subunits of the serine/threonine protein kinases that play key roles in cell cycle control. The roster of known cyclins has expanded significantly in the past year, revealing a large and very diverse family of proteins. Although cyclins were originally characterized by their periodic accumulation during interphase and destruction
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Cyclin A and cyclin B1 overexpression in differentiated thyroid carcinoma
Medical Oncology, 2011Approximately 30% of patients with thyroid nodules have indeterminate or suspicious fine-needle aspiration (FNA) biopsy results. These patients usually undergo thyroidectomy because of cancer risk. Our aim was to determine diagnostic value of cyclin A and cyclin B1 immunohistochemistry added to routine cytology and their expression on histological ...
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Although the basic mechanisms which control the progression through the cell cycle appear to be conserved in all higher eukaryotes, the unique features of the plant developmental programme must be somehow reflected in a plant-specific regulation of the factors which control cell division.
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