Results 131 to 140 of about 13,222,515 (326)
The HIPK2/CDC14B-MeCP2 axis enhances the spindle assembly checkpoint block by promoting cyclin B translation. [PDF]
Partscht P+4 more
europepmc +1 more source
Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2. [PDF]
Helena E. Richardson+4 more
openalex +1 more source
In the study, UBE2C was found to be significantly overexpressed in breast cancer and transcriptionally regulated by FOXM1. Inhibition of UBE2C suppressed proliferation, induced senescence, and sensitized breast cancer cells to doxorubicin. Mechanistically, UBE2C inhibition promoted Parkin‐mediated K63‐linked ubiquitination of TOP2A.
Yihui Yang+12 more
wiley +1 more source
Cartwheel disassembly regulated by CDK1-cyclin B kinase allows human centriole disengagement and licensing. [PDF]
Huang F+5 more
europepmc +1 more source
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun+15 more
wiley +1 more source
RNA Interference Analysis of the Functions of Cyclin B in Male Reproductive Development of the Oriental River Prawn (Macrobrachium nipponense). [PDF]
Zhang W+9 more
europepmc +1 more source
Cyclin G2 Is Up-regulated during Growth Inhibition and B Cell Antigen Receptor-mediated Cell Cycle Arrest [PDF]
Mary C. Horne+6 more
openalex +1 more source
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei+13 more
wiley +1 more source
B-cell chronic lymphocytic leukaemia (B-CLL) originates from B lymphocytes that may differ in the activationlevel, maturation state or cellular subgroups in peripheral blood. Tumour progression in CLL B cells seems to result in gradualaccumulation of the
Antosz Halina+4 more
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