Greatwall depletion from Xenopus oocytes reveals a key role of the cyclin B/CDK1-PP2A-B55 balance in the coordination of meiotic events. [PDF]
Roque S +8 more
europepmc +1 more source
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu +8 more
wiley +1 more source
A distinct phase of cyclin B (Cdc13) nuclear export at mitotic entry in <i>Schizosaccharomyces pombe</i>. [PDF]
Chethan SG +6 more
europepmc +1 more source
Two-Step Mechanism of Cyclin B Degradation Initiated by Proteolytic Cleavage with the 26 S Proteasome in Fish. [PDF]
Tokumoto T +7 more
europepmc +1 more source
Integrated transcriptomic and functional analyses identify CDKN1A as a direct target of ZBED6 in Bama pigs. ZBED6 knockout relieves transcriptional repression of CDKN1A, thereby promoting myogenic differentiation and skeletal muscle development.
Yitian Ma +8 more
wiley +1 more source
Correction: Recombinant cyclin B-Cdk1-Suc1 capable of multi-site mitotic phosphorylation in vitro. [PDF]
PLOS ONE Staff.
europepmc +1 more source
Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long +3 more
wiley +1 more source
Phosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing. [PDF]
Ng HY +4 more
europepmc +1 more source
Spatial Proteomics Identifies Distinct Synovial Microenvironments in Hip and Knee Osteoarthritis
Objective Osteoarthritis (OA) is a heterogeneous joint disease, yet mechanistic insights derive predominantly from knee OA and are often extrapolated to other joints. We investigated joint‐associated differences in the spatial molecular organization of hip and knee OA synovium.
Peng Xie +9 more
wiley +1 more source
miR-21-5p inhibitor enhances the radiosensitivity of human cervical cancer cells via blocking CPEB3-mediated CDK1/cyclin B pathway. [PDF]
Jiao L, Gao Y.
europepmc +1 more source

