Results 161 to 170 of about 470,056 (173)

Increase of cyclin B by overexpression of cystatin α

Cell Biochemistry and Function, 1995
AbstractDegradation of cyclin B was effectively suppressed when cells were treated with ALLN (N‐acetylleucylleucylnorleucinal) which inhibits proteasome, calpain and cysteine proteinase cathepsins. In order to examine which protease degrades cyclin B, the effect of a cathepsin inhibitor, cystatin α, was investigated.
Nobuhiko Katunuma, Jun Ma, Shigeru Sakiyama, Yoshimasa Ike, Takaki Hiwasa   +4 more
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Cyclin A and B functions in the early Drosophila embryo [PDF]

Development, 1999
Abstract In eukaryotes, mitotic cyclins localize differently in the cell and regulate different aspects of the cell cycle. We investigated the relationship between subcellular localization of cyclins A and B and their functions in syncytial preblastoderm Drosophila embryos.
Susanne Trautmann, Cory Trusty, Jun-Yuan Ji, Gerold Schubiger, Lisa A. Stiffler   +4 more
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The expression of SOX11, cyclin D1, cyclin D2, and cyclin D3 in B-cell lymphocytic proliferative diseases

Medical Oncology, 2011
SOX11 is mainly correlated with embryo neurogenesis and remodeling of tissues. D cyclins (cyclin D1, cyclin D2, and cyclin D3) work in cell transformation. We assessed the expression of SOX11, cyclin D1, cyclin D2, and cyclin D3 mRNA in 152 patients with B-cell lymphocytic proliferative diseases (B-LPD) using qRT-PCR and we detected SOX11 protein using
Dan-Xia Zhu, Xin Cao, Hua-Jie Dong, Jianyong Li, Lei Fan, Yin-Hua Wang, Dong-Mei Wang, Wei Xu, Cheng Fang   +8 more
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Factors controlling cyclin B expression

2000
Cyclins control the transition between the phases of the eukaryotic cell cycle as regulatory subunits of the cyclin-dependent kinases (CDKs). Phase-specific activation of the CDK is in part regulated by phase-specific expression of their cyclin component. In most eukaryotic cells including higher plant, B-type cyclin genes are expressed specifically at
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Cyclin D1 Inhibits Mitochondrial Activity in B Cells

Cancer Research, 2011
Abstract Cyclin D1 is a cell cycle regulatory protein that acts at the G1-S transition, following its binding to and activation by the cyclin-dependent kinases 4 or 6. Cyclin D1 is absent from the entire B-cell lineage but is present in a large percentage of 2 types of malignant B-cell hemopathy—mantle cell lymphoma and multiple myeloma—
G, Tchakarska, M, Roussel, X, Troussard, Sola, Brigitte   +3 more
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A Cdc2-sensitive interaction of the UbL domain of XDRP1S with cyclin B mediates the degradation of cyclin B in Xenopus egg extracts

Biochemical and Biophysical Research Communications, 2006
The yeast UbL-UBA protein Dsk2 is thought to act as a shuttle protein that delivers polyubiquitinated proteins to the proteasome. Previously, we identified Xenopus Dsk2-related protein, XDRP1, as a cyclin A-interacting protein. Using Xenopus egg extracts, we further characterized its two isoforms, XDRP1L and XDRP1S, with respect to cyclin binding and ...
Kanae Tanaka, Hideki Kobayashi, Minoru Funakoshi   +2 more
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Sequence of a cDNA encoding a mouse cyclin B protein

Gene, 1991
We report here the nucleotide sequence of a cDNA encoding a mouse (Mus musculus) cyclin B protein. The deduced protein shows 84%, 66% and 49% similarity with human cyclin, Xenopus cyclin B1 and B2, respectively.
Gary D. Paterno, Karen M. Downs
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Cyclin D1 regulates p27Kip1 stability in B cells

Cellular Signalling, 2011
p27(Kip1) is a cyclin-dependent kinase inhibitor that plays a critical role in regulating G(1)/S transition, and whose activity is, in part, regulated through interactions with D-type cyclins. We have generated the BD1-9 cell line, a BaF3 pro-B cells derivative in which cyclin D1 can be induced rapidly and reversibly by ponasterone A.
S, Bustany, G, Tchakarska, Sola, Brigitte   +2 more
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Identification of cyclin A/Cdk2 phosphorylation sites in B‐Myb

European Journal of Biochemistry, 1999
B‐myb is a highly conserved member of the myb proto‐oncogene family that encodes a ubiquitously expressed 110‐kDa sequence‐specific DNA‐binding protein. Transactivation of Myb‐inducible promoters by B‐Myb is repressed by a regulatory domain located at the C‐terminus of the protein. Cyclin A/Cdk2‐mediated phosphorylation apparently releases the negative
Stefano Ferrari, Kaan Toprak, Karl-Heinz Klempnauer, Sebastian Horstmann, Olaf Bartsch   +4 more
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Plant cyclins: a unified nomenclature for plant A-, B- and D-type cyclins based on sequence organization

Plant Molecular Biology, 1996
The comparative analysis of a large number of plant cyclins of the A/B family has recently revealed that plants possess two distinct B-type groups and three distinct A-type groups of cyclins. Despite earlier uncertainties, this large-scale comparative analysis has allowed an unequivocal definition of plant cyclins into either A or B classes. We present
Renaudin, J.P., Doonan, J.H., Freeman, D., Hashimoto, J., Hirt, Heribert, Inzé, Dirk, Jacobs, T., Kouchi, H., Rouzé, Pierre, Sauter, M., Savouré, A., Sorell, D.A., Sundaresan, V., Murray, J.A.H.   +13 more
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