Results 211 to 220 of about 13,222,515 (326)
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan+12 more
wiley +1 more source
Fission yeast Fizzy-related protein srw1p is a G1-specific promoter of mitotic cyclin B degradation
Satoko Yamaguchi+2 more
openalex +2 more sources
CCKB/gastrin receptor mediates synergistic stimulation of DNA synthesis and cyclin D1, D3, and E expression in Swiss 3T3 cells [PDF]
Елена Жукова+4 more
openalex +1 more source
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang+7 more
wiley +1 more source
Conservation and Function of a Potential Substrate-Binding Domain in the Yeast Clb5 B-Type Cyclin
Frederick R. Cross, Matthew D. Jacobson
openalex +1 more source
Novel expression of cyclin-dependent kinase inhibitors in human B-cell precursors [PDF]
Jason R Fink, Tucker W. LeBien
openalex +1 more source
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae+16 more
wiley +1 more source
Cyclin G2 Associates with Protein Phosphatase 2A Catalytic and Regulatory B′ Subunits in Active Complexes and Induces Nuclear Aberrations and a G1/S Phase Cell Cycle Arrest [PDF]
David A. Bennin+7 more
openalex +1 more source
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang+6 more
wiley +1 more source