Results 211 to 220 of about 12,781,724 (361)

Cell-type-specific interacting proteins collaborate to regulate the timing of Cyclin B protein expression in male meiotic prophase.

open access: yesDevelopment, 2023
Baker CC   +7 more
europepmc   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

open access: yesAdvanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li   +13 more
wiley   +1 more source

Cyclin E overexpression in relapsed adult acute lymphoblastic leukemias of B-cell lineage [PDF]

open access: bronze, 1996
R Scuderi   +5 more
openalex   +1 more source

NUDT21‐mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression

open access: yesAdvanced Science, EarlyView.
NUDT21 is overexpressed in colorectal cancer tumors and promotes colorectal cancer progression. NUDT21 promotes the production of a cyclin‐dependent kinase 19 (CDK19) mRNA isoform with a long 3′ UTR, which enhances cytoplasmic export and translation. Truncation of the CDK19 long 3′ UTR phenocopies NUDT21 loss, recapitulating the defects in cholesterol ...
Yeping Yu   +9 more
wiley   +1 more source

Intelligent Thermo‐Self‐Limited Magnetothermia with Heat‐Triggered TERT Silencing for Precision Synergetic Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Telomerase reverse transcriptase (TERT) mRNA induces DNA self‐assembly in cancer cells, boosting the nanoplatform's magnetothermal properties. This magnetothermia then activates the Hsp70 promoter, initiating siRNA synthesis to silence the TERT gene, enhancing cancer treatment.
Liang Zhang   +9 more
wiley   +1 more source

SP17 | AN INTEGRATED DIAGNOSTIC APPROACH COMBINING BONE MARROW BIOPSY AND FLOW CYTOMETRY IN FOUR CHALLENGING CASES OF SMALL B-CELL LYMPHOMA WITH LEUKEMIC PRESENTATION

open access: yesHaematologica
Classification of small B-cell lymphomas with leukemic presentation can be challenging in the absence of nodal involvement. We highlight the value of an integrated diagnostic approach, combining bone marrow (BM) histopathology and flow cytometry (FC ...
F. Adotti   +7 more
doaj  

Identification of variants in cyclin D1 (CCND1) and B-Cell CLL/lymphoma 2 (BCL2) [PDF]

open access: bronze, 2004
Byung Lae Park   +7 more
openalex   +1 more source

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