Results 221 to 230 of about 327,465 (302)
The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C. [PDF]
Dev Cell, 2019 Lara-Gonzalez P +5 more
europepmc +1 more source
Specialization of CDK1 and cyclin B paralog functions in a coenocystic mode of oogenic meiosis. [PDF]
Cell Cycle, 2018 Feng H, Thompson EM.
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
International Journal of Cancer, EarlyView.What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin +9 more
wiley +1 more source
Prognostic and clinicopathological significance of cyclin B expression in patients with breast cancer: A meta-analysis. [PDF]
Medicine (Baltimore), 2017 Sun X +5 more
europepmc +1 more source
International Journal of Cancer, EarlyView.What's New? The CDK4/6 inhibitor ribociclib in combination with an endocrine‐based therapy has demonstrated significant progression‐free and overall survival benefits in patients with advanced/metastatic HR+/HER2‐ breast cancer in the pivotal MONALEESA trials.
Peter A. Fasching +20 more
wiley +1 more source
Overexpression of CKAP4 is Associated with Poor Prognosis in Clear Cell Renal Cell Carcinoma and Functions via Cyclin B Signaling. [PDF]
J Cancer, 2017 Sun CM, Geng J, Yan Y, Yao X, Liu M.
europepmc +1 more source
International Journal of Cancer, EarlyView.What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho +7 more
wiley +1 more source
International Journal of Cancer, EarlyView.Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon +5 more
wiley +1 more source
International Journal of Cancer, EarlyView.What's New? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado +54 more
wiley +1 more source