Results 41 to 50 of about 13,609,830 (345)
Biomolecules, 2021 Botryococcus braunii produce liquid hydrocarbons able to be processed into combustion engine fuels. Depending on the growing conditions, the cell doubling time can be up to 6 days or more, which is a slow growth rate in comparison with other microalgae ...
Xochitl Morales-de la Cruz +6 more
doaj +1 more source
Interaction between Yeast Cdc6 Protein and B-Type Cyclin/Cdc28 Kinases [PDF]
, 1996 During purification of recombinant Cdc6 expressed in yeast, we found that Cdc6 interacts with the critical cell cycle, cyclin-dependent protein kinase Cdc28.
Campbell, Judith L. +4 more
core +1 more source
APC/C–Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs [PDF]
, 2005 In vertebrates, unfertilized eggs are arrested at meiotic metaphase II (meta-II) by cytostatic factor (CSF), with Cdc2 activity maintained at a constant, high level.
Iwabuchi, Mari +3 more
core +1 more source
Intercalative DNA binding of the marine anticancer drug variolin B [PDF]
, 2017 Variolin B is a rare marine alkaloid that showed promising anti-cancer activity soon after its isolation. It acts as a cyclin-dependent kinase inhibitor, although the precise mechanism through which it exerts the cytotoxic effects is still unknown.
Albericio Palomera, Fernando +5 more
core +3 more sources
Phosphorylation of Crm1 by CDK1–cyclin-B promotes Ran-dependent mitotic spindle assembly
Journal of Cell Science, 2013 Summary Mitotic spindle assembly in animal cells is orchestrated by a chromosome-dependent pathway that directs microtubule stabilization. RanGTP generated at chromosomes releases spindle assembly factors from inhibitory complexes with importins, the ...
Zhige Wu +3 more
semanticscholar +1 more source
The ‘destruction box’ of cyclin A allows B-type cyclins to be ubiquitinated, but not efficiently destroyed. [PDF]
The EMBO Journal, 1996 The destruction of mitotic cyclins by programmed proteolysis at the end of mitosis is an important element in cell cycle control. This proteolysis depends on a conserved motif of nine residues known as the 'destruction box', which is located 40-50 residues from the N-terminus. The sequences of the A- and B-type destruction boxes are slightly different,
A Klotzbücher +3 more
openaire +3 more sources
Distinct and Overlapping Requirements for Cyclins A, B, and B3 in Drosophila Female Meiosis
G3: Genes, Genomes, Genetics, 2016 Meiosis, like mitosis, depends on the activity of the cyclin dependent kinase Cdk1 and its cyclin partners. Here, we examine the specific requirements for the three mitotic cyclins, A, B, and B3 in meiosis of Drosophila melanogaster.
Mohammed Bourouh +5 more
doaj +1 more source
Meiotic Maturation of the Mouse Oocyte Requires an Equilibrium between Cyclin B Synthesis and Degradation [PDF]
, 2001 Among the proteins whose synthesis and/or degradation is necessary for a proper progression through meiotic maturation, cyclin B appears to be one of the most important.
Ledan, Emilie +3 more
core +1 more source
Natural Aristolactams and Aporphine Alkaloids as Inhibitors of CDK1/Cyclin B and DYRK1A
Molecules, 2013 In an effort to find potent inhibitors of the protein kinases DYRK1A and CDK1/Cyclin B, a systematic in vitro evaluation of 2,500 plant extracts from New Caledonia and French Guyana was performed. Some extracts were found to strongly inhibit the activity
G. Marti +11 more
semanticscholar +1 more source
International Journal of Oncology, 2013 Kaempferol belongs to the flavonoid family and has been used in traditional folk medicine. Here, we investigated the antitumor effects of kaempferol on cell cycle arrest and autophagic cell death in SK-HEP-1 human hepatic cancer cells.
Wen-Wen Huang +8 more
semanticscholar +1 more source