Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment
Molecular Nutrition &Food Research, EarlyView.Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti +4 more
wiley +1 more source
Phytoestrogen Signal Pathways and Estrogen Signaling in Ovarian Cancer: A Narrative Review
Phytotherapy Research, EarlyView.Phytoestrogen signal pathways targeted in ovarian cancer. ABSTRACT Ovarian cancer (OC) is the second most common gynecological cancer and the leading cause of death from gynecological malignancies. Ovarian cancer mortality rate ranks fifth among cancer‐related deaths in Western societies.
Ozgur Kutuk, Ayse Kaplan
wiley +1 more source
Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein. [PDF]
, 1996 Xiaoyun Zhu +4 more
openalex +1 more source
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells [PDF]
, 1999 Itaru Matsumura
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United European Gastroenterology Journal, EarlyView.ABSTRACT Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic disorder involving any part of the gastrointestinal tract. Ileocecal resection may serve as a more effective treatment option for early CD. However, the potential relationship and mechanisms between the ileocecum and remission induction of CD are still elusive.
Kai Xia +15 more
wiley +1 more source
Brain metastasis in non‐small cell lung cancer: High‐risk factors and predictive models
VIEW, EarlyView.Artificial intelligence (AI) can integrate of data to predict brain metastases (BM) in non‐small cell lung cancer (NSCLC). AI algorithms are employed to analyze these multifaceted datasets, enabling the identification of complex patterns and correlations that may not be apparent through traditional analytical methods.
Chen Gong +7 more
wiley +1 more source
Virus‐Induced Cellular Senescence Causes Pulmonary Sequelae Post‐Influenza Infection
Aging Cell, EarlyView.Genetic or pharmacological depletion of senescent cells during influenza A virus infection led to complete recovery of the airway epithelium, indicating a marked acceleration of the epithelial repair process. Targeting senescent cells may represent a new preventive therapeutic option to reduce post‐influenza chronic lung damage.
Larissa Lipskaia +20 more
wiley +1 more source
Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia. [PDF]
, 1996 Ana I. Robles +7 more
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Aging Cell, EarlyView.In the CA1, microglia are activated to be responsible for synaptic pruning. However, LPS induces a senescent phenotype in microglia, characterized by the elevated levels of p16, as well as the production of SASPs. These senescent microglia mediate the removal of excitatory synapses selectively, resulting in dendritic spine loss and LTP impairment ...
Kai Liu +8 more
wiley +1 more source
Mouse genome engineering uncovers 18 genes dispensable for male reproduction
Andrology, EarlyView.Abstract Background Male infertility is an intricate multifactorial disease involving the interplay between genetic and environmental factors. Genetic anomalies account for more than 15% of all male infertility cases; however, diagnosing them exhibits enormous challenges due to variable symptomatic presentations and limited knowledge of gene functions.
Hsin‐Yi Chang +7 more
wiley +1 more source