Results 181 to 190 of about 141,408 (359)
This study develops a deep learning‐based pipeline named π‐PhenoDrug for cell phenotype‐driven drug activity screening. π‐PhenoDrug integrates cell segmentation, morphological profile construction, and phenotype analysis modules, and it can assess drug effects on living cells in both supervised and unsupervised modes.
Xiao Li+7 more
wiley +1 more source
Demonstration of proliferating cell nuclear antigen (PCNA/Cyclin) in glioma cells.
Kazuo Tabuchi+2 more
openalex +2 more sources
Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley +1 more source
G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells
Lijun Liu+18 more
semanticscholar +1 more source
A complex containing p34cdc2 and cyclin B phosphorylates the nuclear lamin and disassembles nuclei of clam oocytes in vitro. [PDF]
G. Dessev+4 more
openalex +1 more source
Expression of N-terminally truncated cyclin B in the Drosophila larval brain leads to mitotic delay at late anaphase [PDF]
Georgina Rimmington+2 more
openalex +1 more source
Growth Charts for Children With Beckwith–Wiedemann Spectrum
ABSTRACT Beckwith–Wiedemann spectrum (BWSp) is an overgrowth disorder caused by (epi)genetic alterations in chromosome 11p15. This study aimed to develop BWSp‐specific growth charts and explore genotype/phenotype correlations with respect to growth. Heights, weights, and head circumferences were retrospectively collected from 581 individuals with BWSp ...
Saskia M. Maas+11 more
wiley +1 more source
Theoretical dynamics of the cyclin B-MPF system: a possible role for p13suc1
C.D. Thron
openalex +1 more source
D-type cyclin-dependent kinase activity in mammalian cells. [PDF]
H Matsushime+5 more
openalex +1 more source