Results 181 to 190 of about 130,501 (296)

Olig1/2 Drive Astrocytic Glioblastoma Proliferation Through Transcriptional Co-Regulation of Various Cyclins. [PDF]

Genes (Basel)
Tian Y, Wang Z, Sun M, Li J, Zheng W, Yang F, Zhang Z.   +6 more
europepmc   +1 more source

Cyclins and cdks in development and cancer: a perspective

Oncogene, 2005
Amit M. Deshpande, P. Sicinski, P. Hinds
semanticscholar   +1 more source

Cyclin D1 (CCND1); cyclin D2 (CCND2) [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Real‐world progression‐free survival and overall survival in patients with HR+/HER2− advanced breast cancer treated in first‐line with ribociclib, endocrine monotherapy or chemotherapy: Results from the observational RIBANNA study

International Journal of Cancer, EarlyView.
What's New? The CDK4/6 inhibitor ribociclib in combination with an endocrine‐based therapy has demonstrated significant progression‐free and overall survival benefits in patients with advanced/metastatic HR+/HER2‐ breast cancer in the pivotal MONALEESA trials.
Peter A. Fasching, Cosima Brucker, Thomas Decker, Anne Engel, Thomas Göhler, Christian Jackisch, Jan Janssen, Andreas Köhler, Kerstin Lüdtke‐Heckenkamp, Diana Lüftner, Frederik Marmé, Marion van Mackelenbergh, Beate Rautenberg, Marcus Schmidt, Rudolf Weide, Pauline Wimberger, Elena Kisseleff, Christina Pfister, Claudia Quiering, Christian Roos, Achim Wöckel   +20 more
wiley   +1 more source

MEIOC prevents continued mitotic cycling and promotes meiotic entry during mouse oogenesis. [PDF]

Development
Ushuhuda EG, Nguyen JT, Pfaltzgraff NG, Wenner SM, Kofron M, Mikedis MM.   +5 more
europepmc   +1 more source

Cyclins and cell cycle control in cancer and disease.

Genes & cancer, 2012
Mathew C. Casimiro, M. Crosariol, E. Loro, Zhiping Li, R. Pestell   +4 more
semanticscholar   +1 more source

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

International Journal of Cancer, EarlyView.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho, Fabio Nunes de Mello, Ana Carolina Tahira, Gabriel Nakanishi Fortes, Agatha Fischer‐Carvalho, Pedro Jardim Poli, Murilo Sena Amaral, Sergio Verjovski‐Almeida   +7 more
wiley   +1 more source

Capacity for Compensatory Cyclin D2 Response Confers Trametinib Resistance in Canine Mucosal Melanoma. [PDF]

Cancers (Basel)
Wei BR, Verdi V, Zhang S, Mock BA, Shive HR, Simpson RM.   +5 more
europepmc   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Orally Bioavailable Cyclin A/B RxL Inhibitors: Optimization of a Novel Class of Macrocyclic Peptides That Target E2F-High and G1-S-Checkpoint-Compromised Cancers. [PDF]

J Med Chem
Shapiro JA, Dupper NJ, Fraga-Walton B, Bockus AT, Leung SSF, Yang K, Bhatt C, DeMart MK, Baldomero MP, Hernandez L, Fung G, Metobo S, Xie S, Lent BM, Spellmeyer DC, Luna J, Hoang D, Chand M, Gritsenko Y, Gleason CE, Hamkins-Indik F, Zheng J, Odeh R, Nosrati M, He D, Bambal R, Cremin P, Fang J, Levin B, Wang EW, Evangelista M, Earp D, Kreatsoulas C, Singh R, Garcia PD, Aggen JB.   +35 more
europepmc   +1 more source