Results 221 to 230 of about 141,408 (359)
Cuproplasia and cuproptosis, two sides of the coin
Cancer Communications, EarlyView.Abstract Copper is an essential micronutrient in the human body, mainly acting as a crucial cofactor required for a wide range of physiological processes across nearly all cell types. Recent advances revealed that tumor cells seize copper to fulfill their rapid proliferation, metastasis, immune evasion, and so on by reprogramming the copper regulatory ...
Kaizhong Lu +4 more
wiley +1 more source
IJU Case Reports, Volume 6, Issue 1, Page 60-64, January 2023., 2023 Introduction Squamous cell carcinoma arising from a suprapubic cystostomy tract is a rare complication of an indwelling catheter and is caused by long‐term inflammation and mechanical irritation. Prognosis is relatively poor. Biomarkers in the cancer pathway have not been investigated.
Harutake Sawazaki +4 more
wiley +1 more source
The adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2 [PDF]
, 1993 Barbara Faha, E Harlow, Emma Lees
openalex +1 more source
Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Cancer Communications, EarlyView.Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan +13 more
wiley +1 more source
Gut microbiota‐stem cell niche crosstalk: A new territory for maintaining intestinal homeostasis
iMeta, Volume 1, Issue 4, December 2022., 2022 Intestinal stem cells (ISCs) are protected by their niche and are regulated by Wnt, bone morphogenetic protein, and Notch. ISCs and their relationship with intestinal microbiota provide a feasible pathway to alleviate intestinal diseases. Diverse bacteria‐related postbiotics regulate ISCs and maintain their homeostasis.
Ning Ma +3 more
wiley +1 more source
Cancer Communications, EarlyView.Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang +18 more
wiley +1 more source
Isoliquiritigenin Induces Apoptosis via ROS-Mediated Inhibition of p38/mTOR/STAT3 Pathway in Human Melanoma Cells. [PDF]
Biomol Ther (Seoul)Kwon MJ, Raut PK, Jang JH, Chun KS.
europepmc +1 more source
Mouse Development and Cell Proliferation in the Absence of D-Cyclins
Cell, 2004 K. Kozar +11 more
semanticscholar +1 more source
Immunohistochemical Analysis of Cyclin D1 Protein in Hematopoietic Neoplasms with Special Reference to Mantle Cell Lymphoma [PDF]
, 1994 Shigeo Nakamura +13 more
openalex +1 more source
Cancer Communications, EarlyView.Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang +6 more
wiley +1 more source