Results 231 to 240 of about 130,501 (296)

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

open access: yesPhytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou   +9 more
wiley   +1 more source

Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division. [PDF]

open access: yesJ Cell Sci
Palmer N   +11 more
europepmc   +1 more source

Structural mechanism for the recognition of E2F1 by the ubiquitin ligase adaptor Cyclin F. [PDF]

open access: yesProc Natl Acad Sci U S A
Ngoi P   +6 more
europepmc   +1 more source

High-throughput discovery and deep characterization of cyclin-CDK docking motifs

open access: yes
Örd M   +10 more
europepmc   +1 more source
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