Results 231 to 240 of about 141,408 (359)

HU308 Mitigates Osteoarthritis by Stimulating Sox9‐Related Networks of Carbohydrate Metabolism

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 154-170, January 2023., 2023
ABSTRACT Osteoarthritis (OA) is characterized by progressive, irreversible erosion of articular cartilage accompanied by severe pain and immobility. This study aimed to assess the effect and mechanism of action of HU308, a selective cannabinoid receptor type 2 (CB2) agonist, in preventing OA‐related joint damage. To test the assumption that HU308 could
Idan Carmon, Lital Zecharyahu, Jinan. Elayyan, Sai R. K. Meka, Eli Reich, Leonid Kandel, Andras Bilkei‐Gorzo, Andreas Zimmer, Raphael Mechoulam, Nataly Kravchenko‐Balasha, Mona Dvir‐Ginzberg   +10 more
wiley   +1 more source

Investigating associations between JAK inhibition and venous thromboembolism by systematic mining of large-scale datasets. [PDF]

Inflammopharmacology
Haysen SR, Nielsen AL, Qvist P, Kragstrup TW.   +3 more
europepmc   +1 more source

Simian virus 40 large T antigen associates with cyclin A and p33cdk2 [PDF]

, 1993
J P Adamczewski, Julian Gannon, Tim Hunt
openalex   +1 more source

Ten quick tips for ensuring machine learning model validity. [PDF]

PLoS Comput Biol
Goh WWB, Kabir MN, Yoo S, Wong L.
europepmc   +1 more source

Modeling the cell division cycle: cdc2 and cyclin interactions.

, 1991
John J. Tyson
openalex   +1 more source

In vitro fusion of endocytic vesicles is inhibited by cyclin A-cdc2 kinase. [PDF]

, 1993
Philip Woodman, J P Adamczewski, Tim Hunt, W. G. Warren   +3 more
openalex   +1 more source

FLOT1 Is a Novel Serum Biomarker of Ovarian Cancer Targeted by N6‐methyladenosine Modification Inhibition

Cell Biology International, EarlyView.
ABSTRACT Ovarian cancer (OC) is a deadly disease and lacks a precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin‐1 (FLOT1) in OC tissue. To improve diagnostic sensitivity and accuracy, we evaluated the serum level of FLOT1 in OC patients and found that the serum concentration of FLOT1 as well as CA125 was
Bin Guan, Qi Lu, Junyu Chen, Jingyi Fang, Zhenyu Liu, Wei Li, Lingyun Zhang, Guoxiong Xu   +7 more
wiley   +1 more source

Vascular perfusion differs in two distinct PDGFRβ‐positive zones within the ischemic core of male mice 2 weeks following photothrombotic stroke

Journal of Neuroscience Research, Volume 101, Issue 2, Page 278-292, February 2023., 2023
Blood vessels in the ischemic core and peri‐lesion are capable of flow 2 weeks post‐photothrombotic stroke. There are two PDGFRβ‐positive zones within the ischemic core, one which resembles fibrotic scarring, adjacent to a GFAP‐positive peri‐lesion, whereas the other is primarily vessel associated.
Gary P. Morris, Emma K. Gowing, Jo‐Maree Courtney, Hannah E. Coombe, Natalie E. King, Sarah S. J. Rewell, David W. Howells, Andrew N. Clarkson, Brad A. Sutherland   +8 more
wiley   +1 more source

Long‑term progression‑free survival in HR+/HER2+ advanced breast cancer with combination therapy with a CDK4/6 inhibitor and first‑line maintenance therapy: A case report. [PDF]

Oncol Lett
Cai Y, Zhang J, Duan H, Liu F.
europepmc   +1 more source

Distribution of Troy (Tnfrsf19) in the Gastric Gland During Postnatal Development: Effects of Early Weaning

Cell Biology International, EarlyView.
ABSTRACT This study investigates the distribution and role of the stem cell marker Troy (Tnfrsf19) in the gastric mucosa of rats during postnatal development and the effects of early weaning. Troy, previously identified as a reserve stem cell marker in adult gastric tissues, is examined across various developmental stages from birth to adulthood.
Isadora Campos Rattes, Kethleen Mesquita da Silva, Patrícia Gama   +2 more
wiley   +1 more source