Results 21 to 30 of about 3,707,282 (391)
Simultaneous cyclization and derivatization of peptides using cyclopentenediones [PDF]
, 2017 Unprotected linear peptides containing N-terminal cysteines and another cysteine residue can be simultaneously cyclized and derivatized using 2,2-disubstituted cyclopentenediones. High yields of cyclic peptide conjugates may be obtained in short reaction
Agramunt, Jordi +4 more
core +2 more sources
Gastroenterology Research and Practice, 2012 Aim. The study was to investigate the metabolic profile of urine metabolites and to elucidate their clinical significance in patients with colorectal cancer. Methods. Colorectal cancers from early stage and advanced stage were used in this study.
Jin-Lian Chen +6 more
doaj +1 more source
Indonesian Journal of Chemistry, 2010 Two steps transformation of (+)-citronellal, cyclization and hydrogenation, on ZnBr2/γ-Al2O3 and Ni/γ-Al2O3 catalyst have been realized with the selectivity to cyclization products (isopulegols) was very high (yield up to ~92.58%) over ZnBr2/γ-Al2O3 ...
Elvina Dhiaul Iftitah +3 more
doaj +1 more source
Asymmetric Redox-Neutral Radical Cyclization Catalyzed by Flavin-Dependent ‘Ene’-Reductases
Nature Chemistry, 2019 Flavin-dependent ‘ene’-reductases (EREDs) are exquisite catalysts for effecting stereoselective reductions. Although these reactions typically proceed through a hydride transfer mechanism, we recently found that EREDs can also catalyse reductive ...
M. Black +6 more
semanticscholar +1 more source
DNA cyclization and looping in the wormlike limit: normal modes and the validity of the harmonic approximation [PDF]
, 2015 For much of the last three decades Monte Carlo-simulation methods have been the standard approach for accurately calculating the cyclization probability, $J$, or J factor, for DNA models having sequence-dependent bends or inhomogeneous bending ...
Alexandrowicz +43 more
core +3 more sources
A generalized theory of semiflexible polymers [PDF]
, 2005 DNA bending on length scales shorter than a persistence length plays an integral role in the translation of genetic information from DNA to cellular function. Quantitative experimental studies of these biological systems have led to a renewed interest in
B. Alberts +10 more
core +3 more sources
Chemoselective Peptide Cyclization and Bicyclization Directly on Unprotected Peptides.
Journal of the American Chemical Society, 2019 Cyclic peptides are drawing wide attentions as potential medium-sized modulators of biomolecular interactions with large binding surfaces. Simple but effective peptide cyclization methods are needed to construct cyclic peptide libraries by both peptide ...
Yue Zhang +3 more
semanticscholar +1 more source
Recent Advances in the Biosynthesis of Carbazoles Produced by Actinomycetes
Biomolecules, 2020 Structurally diverse carbazole alkaloids are valuable due to their pharmaceutical properties and have been isolated from nature. Experimental knowledge on carbazole biosynthesis is limited. The latest development of in silico analysis of the biosynthetic
Masaya Kobayashi, Tomohisa Kuzuyama
doaj +1 more source
Applied Sciences, 2023 New derivatives of 5-phenyl-1,3,4-oxadiazole substituted at position 2 with (bromomethyl)phenyl or bromoalkyl groups were obtained via microwave-assisted cyclodehydration of unsymmetrical N,N′-diacylhydrazines.
Marcin Łuczyński, Agnieszka Kudelko
doaj +1 more source
Mechanism, reactivity, and selectivity of nickel-catalyzed [4 + 4 + 2] cycloadditions of dienes and alkynes. [PDF]
, 2014 Density functional theory (DFT) calculations with B3LYP and M06 functionals elucidated the reactivities of alkynes and Z/E selectivity of cyclodecatriene products in the Ni-catalyzed [4 + 4 + 2] cycloadditions of dienes and alkynes.
Baran, Phil S +4 more
core +2 more sources