Results 41 to 50 of about 2,874,801 (150)

IBD-mediated oxidative cyclization of pyrimidinylhydrazones and concurrent Dimroth rearrangement: Synthesis of [1,2,4]triazolo[1,5-c]pyrimidine derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2013
Oxidative cyclization of 6-chloro-4-pyrimidinylhydrazones 4 with iodobenzene diacetate (IBD) in dichloromethane gives rise to [1,2,4]triazolo[4,3-c]pyrimidine derivatives 5a–o.
Caifei Tang, Zhiming Li, Quanrui Wang
doaj   +1 more source

All-carbon [3 + 2] cycloaddition in natural product synthesis

open access: yesBeilstein Journal of Organic Chemistry, 2020
Many natural products possess interesting medicinal properties that arise from their intriguing chemical structures. The highly-substituted carbocycle is one of the most common structural features in many structurally complicated natural products ...
Zhuo Wang, Junyang Liu
doaj   +1 more source

Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones

open access: yesMolecules, 2005
Three convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are
Patrice Vanelle   +3 more
doaj   +1 more source

Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt

open access: yesBeilstein Journal of Organic Chemistry, 2020
A synthesis of fluorinated pyrimidines under mild conditions from amidine hydrochlorides and the recently described potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained.
Tobias Lucas   +2 more
doaj   +1 more source

Synthesis of vinyldihydropyran by cooperative catalysis [PDF]

open access: yesJournal of the Serbian Chemical Society, 2016
5-Unsaturated aldehydes with a suitably positioned allylic halide, or phosphate, leaving group undergo doubly-catalyzed cyclization to give dihydropyran derivatives.
Vulović Bojan   +3 more
doaj   +1 more source

Recent Progress in the Cyclization Reactions Using Carbon Dioxide

open access: yes, 2017
Carbon dioxide is a cheap, abundant and renewable C 1 feedstock. Methodology study on the transformation of carbon dioxide into highly value-added chemicals has become one of the most active topics in organic chemistry.
Wen-Zhen Zhang   +3 more
semanticscholar   +1 more source

Sequentially Palladium-Catalyzed Processes in One-Pot Syntheses of Heterocycles

open access: yesApplied Sciences, 2015
Sequentially Pd-catalyzed processes are excellent entries to heterocycle synthesis. The broad mechanistic variety combined with often very mild reaction conditions allow the concatenation of elementary organic and organometallic steps to novel sequences ...
Timo Lessing, Thomas J. J. Müller
doaj   +1 more source

Iodine-mediated synthesis of 3-acylbenzothiadiazine 1,1-dioxides

open access: yesBeilstein Journal of Organic Chemistry, 2016
An iodine-mediated synthesis of 3-acylbenzothiadizine 1,1-dioxides is described. A range of electronically diverse acetophenones reacted well with several 2-aminobenzenesulfonamides, affording 3-acylbenzothiadiazine 1,1-dioxides in good yields.
Long-Yi Xi   +4 more
doaj   +1 more source

A novel and efficient method to prepare 2-aryltetrahydrofuran-2-ylphosphonic acids

open access: yesBeilstein Journal of Organic Chemistry, 2010
A novel one-pot method was developed for the synthesis of the title compounds starting from 4-chloro-1-aryl-1-butanones 1, phosphorus trichloride and acetic acid. The end products 2 were obtained in 20–94% yield.
Vsevolod V. Komissarov   +2 more
doaj   +1 more source

Structural determinants of reductive terpene cyclization in iridoid biosynthesis

open access: yesNature Chemical Biology, 2015
The carbon skeleton of ecologically and pharmacologically important iridoid monoterpenes is formed in a reductive cyclization reaction unrelated to canonical terpene cyclization.
Hajo Kries   +7 more
semanticscholar   +1 more source

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