Results 41 to 50 of about 2,874,801 (150)
Oxidative cyclization of 6-chloro-4-pyrimidinylhydrazones 4 with iodobenzene diacetate (IBD) in dichloromethane gives rise to [1,2,4]triazolo[4,3-c]pyrimidine derivatives 5a–o.
Caifei Tang, Zhiming Li, Quanrui Wang
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All-carbon [3 + 2] cycloaddition in natural product synthesis
Many natural products possess interesting medicinal properties that arise from their intriguing chemical structures. The highly-substituted carbocycle is one of the most common structural features in many structurally complicated natural products ...
Zhuo Wang, Junyang Liu
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Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones
Three convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are
Patrice Vanelle+3 more
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Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt
A synthesis of fluorinated pyrimidines under mild conditions from amidine hydrochlorides and the recently described potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained.
Tobias Lucas+2 more
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Synthesis of vinyldihydropyran by cooperative catalysis [PDF]
5-Unsaturated aldehydes with a suitably positioned allylic halide, or phosphate, leaving group undergo doubly-catalyzed cyclization to give dihydropyran derivatives.
Vulović Bojan+3 more
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Recent Progress in the Cyclization Reactions Using Carbon Dioxide
Carbon dioxide is a cheap, abundant and renewable C 1 feedstock. Methodology study on the transformation of carbon dioxide into highly value-added chemicals has become one of the most active topics in organic chemistry.
Wen-Zhen Zhang+3 more
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Sequentially Palladium-Catalyzed Processes in One-Pot Syntheses of Heterocycles
Sequentially Pd-catalyzed processes are excellent entries to heterocycle synthesis. The broad mechanistic variety combined with often very mild reaction conditions allow the concatenation of elementary organic and organometallic steps to novel sequences ...
Timo Lessing, Thomas J. J. Müller
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Iodine-mediated synthesis of 3-acylbenzothiadiazine 1,1-dioxides
An iodine-mediated synthesis of 3-acylbenzothiadizine 1,1-dioxides is described. A range of electronically diverse acetophenones reacted well with several 2-aminobenzenesulfonamides, affording 3-acylbenzothiadiazine 1,1-dioxides in good yields.
Long-Yi Xi+4 more
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A novel and efficient method to prepare 2-aryltetrahydrofuran-2-ylphosphonic acids
A novel one-pot method was developed for the synthesis of the title compounds starting from 4-chloro-1-aryl-1-butanones 1, phosphorus trichloride and acetic acid. The end products 2 were obtained in 20–94% yield.
Vsevolod V. Komissarov+2 more
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Structural determinants of reductive terpene cyclization in iridoid biosynthesis
The carbon skeleton of ecologically and pharmacologically important iridoid monoterpenes is formed in a reductive cyclization reaction unrelated to canonical terpene cyclization.
Hajo Kries+7 more
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