Results 41 to 50 of about 831,285 (343)

Substituents Regulate the Cyclization of Conjugated Alkynes to Accurately Construct Cyclo-(E)-[3]dendralenes

Molecules, 2023
Substituent-regulated cyclization of conjugated alkynes with acid catalysis was developed in this paper, and it provides a straightforward synthesis of cyclic-(E)-[3]dendralenes.
Yun-Tao Xia, Ya-Xin Li, Tong-Tong Bi, Wei Lian, Xia Wang, Meng Yan, Tao Guo   +6 more
doaj   +1 more source

Free radical cyclizations [PDF]

Pure and Applied Chemistry, 1967
Abstract
openaire   +1 more source

Exact theory of kinkable elastic polymers [PDF]

, 2004
The importance of nonlinearities in material constitutive relations has long been appreciated in the continuum mechanics of macroscopic rods. Although the moment (torque) response to bending is almost universally linear for small deflection angles, many ...
A. Y. Grosberg, C. A. Sucato, D. Shore, E. N. Trifonov, G. B. Arfken, H. Yamakawa, J. Bernet, J. J. Sakurai, L. D. Landau, O. Kratky, P. C. Nelson, Paul A. Wiggins, Philip C. Nelson, R. P. Feynman, Rob Phillips   +14 more
core   +5 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Hypervalent iodine-mediated cyclization of bishomoallylamides to prolinols

Beilstein Journal of Organic Chemistry
A change in mechanism was observed in the hypervalent iodine-mediated cyclization of N-alkenylamides when the carbon chain between the alkene and the amide increased from two to three atoms.
Smaher E. Butt, Konrad Kepski, Jean-Marc Sotiropoulos, Wesley J. Moran   +3 more
doaj   +1 more source

Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones

Molecules, 2005
Three convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are
Patrice Vanelle, Michel P. Crozet, Pascal George, Maxime D. Crozet   +3 more
doaj   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

ELECTROPHILIC CYCLIZATION OF DITERPENOIDS [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2006
A review of diterpenoid cyclization initiated by electrophilic reagents is provided. Conventional protonic and Lewis acids are examined along with superacids as initiators of cyclization cascade.
Veaceslav Kulciţki, Marina Grinco, Pavel Vlad, Nicon Ungur   +3 more
doaj  

Oxidative radical ring-opening/cyclization of cyclopropane derivatives

Beilstein Journal of Organic Chemistry, 2019
The ring-opening/cyclization of cyclopropane derivatives has drawn great attention in the past several decades. In this review, recent efforts in the development of oxidative radical ring-opening/cyclization of cyclopropane derivatives, including ...
Yu Liu, Qiao-Lin Wang, Zan Chen, Cong-Shan Zhou, Bi-Quan Xiong, Pan-Liang Zhang, Chang-An Yang, Quan Zhou   +7 more
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source