Results 111 to 120 of about 140,419 (292)

Cycloaddition of Diphenylnitrilimine to 1,5-Benzodiazepines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2000
The cycloaddition reaction of diphenylnitrilimine on the 1,5-benzodiazepines has been studied. New molecules of triazolobenzodiazepines type have been isolated and characterized.
Rachid Zinber, Redouane Achour, Ahmed Jalal El Hajji, Asmaa Hakan, Mohammed Zoubair Cherkaui   +4 more
doaj  

Synthesis of Polysubstituted Naphthalenes via Metal‐Free Borylative Cyclization of o‐Alkynylstyrenes

Advanced Synthesis &Catalysis, EarlyView.
Abstract A selective, metal‐free method for the synthesis of boron‐functionalized polysubstituted naphthalenes via BCl3‐mediated cyclization of α‐substituted o‐alkynylstyrenes is described. The reaction exhibits broad substrate scope, tolerating various groups such as ethers, sulfides and halogens, and delivers high yields under mild conditions, even ...
Marcos Humanes, Manuel A. Fernández‐Rodríguez, Patricia García‐García   +2 more
wiley   +1 more source

Recent Applications of the Simple Hydrocarbon Cyclooctatetrene as a Starting Material for Complex Molecule Synthesis [PDF]

, 2012
Cyclooctatetraene [COT], a simple non-aromatic cyclic polyene, is capable of undergoing a variety of oxidation and cycloaddition reactions to afford polycyclic structures.
Donaldson, William, Glaeske, Kevin W
core   +2 more sources

Modular Synthesis of 2,3,4,6‐Tetrasubstituted Thieno[2,3‐c]furans Based on Formal [3+2] Cycloaddition Utilizing [1,2]‐Phospha‐Brook Rearrangement / Brønsted Base‐Mediated Cyclization Strategy

Advanced Synthesis &Catalysis, EarlyView.
Abstract A modular synthesis of 2,3,4,6‐tetrasubstituted thieno[2,3‐c]furans, which employs a formal [3+2] cycloaddition utilizing the [1,2]‐phospha‐Brook rearrangement and a subsequent Brønsted base‐mediated cyclization, has been established, providing an efficient access to a wide range of densely functionalized thieno[2,3‐c]furans that are otherwise
Azusa Kondoh, Kohei Aita, Masahiro Terada   +2 more
wiley   +1 more source

Mechanochemistry: Fundamental Principles and Applications

Advanced Science, EarlyView.
In this review, the physicochemical principles of mechanochemistry are first clarified. Based on this foundation, the research basis and cutting‐edge scientific achievements in four areas are introduced: solid‐state organic chemistry, polymers, interface science, and biomechanochemistry.
Liang Dong, Luofei Li, Huiyan Chen, Yi Cao, Hai Lei   +4 more
wiley   +1 more source

Alkyne–Alkene [2 + 2] cycloaddition based on visible light photocatalysis

Nature Communications, 2020
[2 + 2] cycloaddition of alkynes with alkenes would normally require UV light irradiation. Here, the authors report an alkyne–alkene [2 + 2] cycloaddition based on visible light energy transfer photocatalysis, both inter- and intramolecularly, to afford ...
Sujin Ha, Yeji Lee, Yoonna Kwak, Akash Mishra, Eunsoo Yu, Bokyeong Ryou, Cheol-Min Park   +6 more
doaj   +1 more source

Affinity‐Based Isolation and One‐Pot Analysis of Extracellular Vesicles from Biofluids Using Phase Separated Zwitterionic Coacervates

Advanced Science, EarlyView.
This study presents a novel method for affinity‐based isolation and analysis of extracellular vesicles from biofluids using phase‐separated zwitterionic coacervates functionalized with a membrane‐sensing peptide. This technology minimizes nonspecific binding, enabling high‐yield isolation and direct one‐pot biomarker profiling.
Francesca Torrini, Roberto Frigerio, Jonathan Garlipp, Philippe Lenzen, Karl Normak, Carolina Paganini, Marina Cretich, Alessandro Gori, Paolo Arosio   +8 more
wiley   +1 more source

Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao, Zhili Wang, Hyoyong Kim, Hui Kong, Junseok Lee, Jacqueline Ziqian Yang, Anmin Wang, Ryan Y. Zhang, Yong Ju, Jina Kim, Bing Feng, Dejun Liu, Yating Zhang, Zhenfang Wang, Yandong Zhang, Shujing Guo, Dekang Gao, James S. Tomlinson, Renjun Pei, Jipeng Wan, Stephen J. Pandol, Myung‐Shin Sim, Sungyong You, Ding Ma, Shaohua Lu, Na Sun, Hsian‐Rong Tseng, Yazhen Zhu   +27 more
wiley   +1 more source

Development of a Novel Epoxide-Containing Trimethylenemethane Precursor for Palladium-Catalyzed Cycloadditions [PDF]

, 2019
Pd(0)-catalyzed trimethylenemethane (TMM) cycloaddition reactions have been used extensively to generate disubstituted 5-membered rings with high levels of regioselectivity, chemoselectivity, and stereoselectivity.
Paterson, Mara
core   +2 more sources

A Reversible and Dynamic Surface Functionalization for Fluidity Controlled Multivalent Recognition of Lectins and Bacteria

Advanced Science, EarlyView.
A reversible wet chemical surface functionalization results in dynamic multivalent receptors showing ligand‐specific high affinity for lectins and bacteria. Abstract The paper reports the design of multivalent bacterial receptors based on reversible self‐assembled monolayers (rSAMs) on gold and glass substrates, mimicking the ligand display on host ...
Thomas Hix‐Janssens, Adam Tillo, Hanna Isaieva, Zita Lopes da Silva, Zahra Fatahi, Michele Larocca, Gustav Sedelius, Sara Björk Sigurdardóttir, Yulia Sergeeva, Tiba Al‐Dujaili, Julia R. Davies, Kushagr Punyani, Börje Sellergren   +12 more
wiley   +1 more source