Prediction of Ligand Binding to Transthyretin Using Machine Learning Algorithms and Low-Dimensional Molecular Descriptors: A Tox24 Challenge Study. [PDF]
Stefaniak F.
europepmc +1 more source
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad +6 more
wiley +1 more source
Recent Advancements in Information Ratchet Design. [PDF]
Incarbone S, De Gioia L.
europepmc +1 more source
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta +17 more
wiley +1 more source
Radiolabelled Cyclodextrins for the Positron Emission Tomography Imaging of Breast Cancer: Preclinical Perspectives. [PDF]
Sass T +10 more
europepmc +1 more source
Resveratrol: Advance on the Most Recent Research From 2021 to 2025
This review summarizes recent progress in resveratrol research (2021–2025), highlighting its natural sources, bioactivities, clinical evidence, and safety profiles. Resveratrol exerts multi‐target effects through the regulation of oxidative stress, inflammation, mitochondrial function, and gut microbiota.
Quanyong Wu +4 more
wiley +1 more source
Curcumin Delivery Systems: From Importance and Microencapsulation Techniques to Molecular Docking and Dynamics for Rational Formulation Design. [PDF]
Crețu R +4 more
europepmc +1 more source
Abstract Glucagon is a well‐established therapeutic peptide, widely used to treat hypoglycemia. Like many peptide drugs, it offers advantages such as specificity, biocompatibility, and high affinity for receptor targets, but suffers from limited physical and chemical stability.
Angelo Santoro +4 more
wiley +1 more source
Redirecting Excited‐State Proton Transfer Through Supramolecular Polymerization in Nanoconfinement
Supramolecular confinement redirects the excited‐state proton transfer pathway of an amphoteric emitter. In water, the molecule undergoes ESPD, whereas co‐assembly with γ‐cyclodextrin forms nanotubes that template slip‐stacked emitter pairs and enable ESIMPT. Structural and photophysical characterization of the assemblies shows that the preorganization
Luis C. Pantaleone +8 more
wiley +2 more sources
PPARγ Agonistic Activity of Mimulone and Diplacone Encapsulated in Liposomes and Cyclodextrin Complexes. [PDF]
Nykodýmová D +4 more
europepmc +1 more source

