Results 31 to 40 of about 221,688 (338)

In vitro anti-inflammatory activity of the Artemisia montana leaf ethanol extract in macrophage RAW 264.7 cells

Food and Agricultural Immunology, 2018
Artemisia is one of the largest genera of the family Asteraceae or Compositae, consisting of 500 species. Some Artemisia species, such as Artemisia afra, A. sacrorum, and A.
Seong Hun Jeong, Jisu Kim, Hyeyoung Min
doaj   +1 more source

POTENSI KOMBINASI EKSTRAK AKAR SIDAGURI (Sida rhombifolia L.) DAN GETAH JARAK (Jatropha curcas L.) SEBAGAI BAHAN DEVITALISASI

ODONTO: Dental Journal, 2019
Background: Arsenic paste was used to devitalize dental pulp in some problems before surgical, but it has been proven to have many hazardous effects. So, other alternative drugs are needed that are equally effective but safer. Jatropha (Jatropha curcas L.
Maria Tanumihadja, Indrya Kirana Mattulada, Nurhayaty Natsir, Lukman Muslimin   +3 more
doaj   +1 more source

Systematic study of constitutive cyclo-oxygenase-2 expression: role of NFκB and NFAT transcriptional pathways [PDF]

, 2015
Cyclooxygenase-2 (COX-2) is an inducible enzyme that drives inflammation and is the therapeutic target for widely used nonsteroidal antiinflammatory drugs (NSAIDs).
Ahmetaj-Shala, B, Berglund, LM, Chan, MV, Garcia-Vaz, E, Gomez, MF, Herschman, HR, Jiao, J, Kirkby, NS, Mitchell, JA, Verdu, EF, Wallace, JL, Zaiss, AK   +11 more
core   +1 more source

Pharmacological hypotheses: Is acetaminophen selective in its cyclooxygenase inhibition?

Pharmacology Research & Perspectives, 2021
The precise mechanistic action of acetaminophen (ACT; paracetamol) remains debated. ACT’s analgesic and antipyretic actions are attributed to cyclooxygenase (COX) inhibition preventing prostaglandin (PG) synthesis.
Christopher J. Esh, Bryna C. R. Chrismas, Alexis R. Mauger, Lee Taylor   +3 more
doaj   +1 more source

Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. [PDF]

, 2011
Based on its capacity to inhibit in vitro HIV-1 replication in T cells and the release of pro-inflammatory cytokines in monocytes, the prenylated heterodimeric phloroglucinyl α-pyrone arzanol was identified as the major anti-inflammatory and anti-viral ...
Appendino G, Bauer J, Dehm F, Koeberle A, Northoff H, Pollastro F, ROSSI, ANTONIETTA, SAUTEBIN, LIDIA, Werz O.   +8 more
core   +1 more source

Methyl Salicylate Lactoside Protects Neurons Ameliorating Cognitive Disorder Through Inhibiting Amyloid Beta-Induced Neuroinflammatory Response in Alzheimer’s Disease

Frontiers in Aging Neuroscience, 2018
Neuroinflammatory reactions mediated by microglia and astrocytes have been shown to play a key role in early progression of Alzheimer’s disease (AD). Increased evidences have demonstrated that neurons exacerbate local inflammatory reactions by producing ...
Jinze Li, Xiaowei Ma, Xiaowei Ma, Yu Wang, Chengjuan Chen, Min Hu, Linlin Wang, Junmin Fu, Gaona Shi, Dongming Zhang, Tiantai Zhang   +10 more
doaj   +1 more source

Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides

Biomolecules, 2021
Tripterygium wilfordii glycosides (TWG) is a traditional Chinese medicine with effectiveness against rheumatoid arthritis (RA), supported by numerous clinical trials.
Kehong Zhang, Simona Pace, Paul M. Jordan, Lukas K. Peltner, Alexander Weber, Dagmar Fischer, Robert K. Hofstetter, Xinchun Chen, Oliver Werz   +8 more
doaj   +1 more source

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney [PDF]

, 2015
BACKGROUND: The role of cyclooxygenase(COX)-1 and COX-2 in the saluretic and renin-angiotensin responses to loop diuretics in the cat is unknown. We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal ...
A Hayes, B Mann, B Rose, B Rose, B Rose, CM Hao, DA Heller, DO Stichtenoth, F Catella-Lawson, F Nantel, G Giovanni, H Syme, H. Syme, J Hippisley-Cox, J Peti-Peterdi, J. Elliott, J. N. King, JA Jakobsen, K Schumacher, K. Smith, KA Kirchner, KL Therland, KN Khan, KN Khan, L Pelligand, L Pelligand, L. Pelligand, M Komhoff, M Meskell, M Sabbatini, N. Suemanotham, P. Lees, PA Friedman, RC Harris, RC Harris, RE Jepson, S Yu, V Campean, V Sreenivasan, VB Schmid, W. Seewald, WA Corsini, XR He   +42 more
core   +2 more sources

The choreography of cyclooxygenases in the kidney [PDF]

Journal of Clinical Investigation, 2002
Nihil est ab omni parte beatum. (No blessing is unmixed.) —Horace Consideration of the cardiovascular effects of cyclooxygenase (COX) inhibition has generated much heat and some light since the emergence of selective inhibitors of COX2 onto the US market in January 1999.
openaire   +3 more sources

Production of lipid mediators across different disease stages of dextran sodium sulfate-induced colitis in mice

Journal of Lipid Research, 2018
Although several studies have revealed the role of different lipid mediators in colitis, the comprehensive analysis of their production across different phases of colitis remained unclear.
Taiki Hamabata, Tatsuro Nakamura, Sakura Masuko, Shingo Maeda, Takahisa Murata   +4 more
doaj   +1 more source