Results 11 to 20 of about 106,475 (259)
Interaction of meloxicam and phenylbutazone on the level of cyclooxygenase-2 in mice [PDF]
Iraqi Journal of Veterinary Sciences, 2022 The reason for the recent study was to inspect the therapeutic efficacy of meloxicam and phenylbutazone alone with their analgesic interaction and their subsequent inhibitory interaction at the level of cyclooxygenase-2 in mice.
Yaareb J. Mousa +2 more
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Ancient Science of Life, 2018 Background: Agnimantha is a constituent of the bṛhatpañcamūla (the roots drugs of 5 tree species) which in turn is a part of daśamūla used in Ayurvedic pharmaceutical practices.
Narasimha Baba Brindavanam +3 more
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Differential expression of cyclooxygenase 1 and cyclooxygenase 2 in the bovine oviduct [PDF]
Journal of Endocrinology, 2006 The aim of the present study was to investigate the enzymes for the local prostaglandin (PG) biosynthesis present in the bovine oviduct during the estrous cycle to influence early reproductive events. Bovine oviducts were classified into four phases: pre-ovulatory, post-ovulatory, early-to-mid luteal, and late luteal phase, subdivided further into ipsi-
Simone, Odau +3 more
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Regulated Spatial Distribution of Cyclooxygenases and Lipoxygenases in Crohn's Ulcer
Mediators of Inflammation, 2006 Background and Aims. Arachidonic acid metabolism actively participates in the initiation, climaxing, and resolution phases of inflammation, and its close connection with inflammatory bowel diseases has been only recently discovered.
Yao Mao, Jian'an Ren, Jieshou Li
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Journal of Applied Oral Science, 2010 Prostaglandins control osteoblastic and osteoclastic function under physiological or pathological conditions and are important modulators of the bone healing process.
Ricardo Nogueira Fracon +3 more
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Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in Human Breast Cancer [PDF]
JNCI: Journal of the National Cancer Institute, 1998 Numerous studies have demonstrated that the levels of prostaglandins are greater in various cancers, including breast cancer and colon cancer, than in normal tissues. In particular, the inducible form of cyclooxygenase (COX), the rate-limiting enzyme in prostaglandin biosynthesis, is overexpressed in colon tumors.
D, Hwang +3 more
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Expression and correlation of COX-2 and NUCB1 in colorectal adenocarcinoma [PDF]
PeerJ, 2023 Objective To investigate the expression and correlation of COX-2 and NUCB1 in colorectal adenocarcinoma and adjacent tissues. Methods The expression of COX-2 and NUCB1 and their effects on prognosis were predicted using bioinformatics ...
Yuanyuan Zhang +5 more
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Cyclooxygenase-1-selective inhibitor SC-560
Acta Crystallographica Section E, 2009 In the title compound, 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole (SC-560), C17H12ClF3N2O, a COX-1-selective inhibitor, the dihedral angles between the heterocycle and the chlorobenzene and methoxybenzene rings are 41.66
Charles D. Loftin +3 more
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Journal of Neuroinflammation, 2020 Background Cyclooxygenase-2 (COX-2), which is rapidly upregulated by inflammation, is a key enzyme catalyzing the rate-limiting step in the synthesis of several inflammatory prostanoids.
Stal Shrestha +23 more
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Antiplatelet activity of deferiprone through cyclooxygenase-1 inhibition
Platelets, 2020 Thalassemia patients are susceptible to both iron overload and thromboembolism. Deferiprone is an iron chelator that shows an antiplatelet activity and thus may alleviate platelet hyperactivation in thalassemia.
Ngan Thi Tran +4 more
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