Results 41 to 50 of about 22,053,927 (171)
Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity
Cancer Cell International, 2015 Cyclooxygenase-2 (COX-2), an inducible form of the enzyme that catalyzes the first step in the synthesis of prostanoids, is associated with inflammatory diseases and carcinogenesis, which is suspected to promote angiogenesis and tissue invasion of tumors
Bing Liu, Liyan Qu, Shigui Yan
semanticscholar +1 more source
Value of COX-2 and HER-2 in Judging Condition and Prognosis in Non-Small Cell Lung Cancer Patients
Cancer Biology & Medicine, 2010 OBJECTIVE To investigate the expressions of cyclooxygenase 2 (COX-2) and human epidermal growth factor receptor-2 (HER-2) in non-small cell lung cancer (NSCLC) and their clinical significance in identifying the progression and prognosis of the NSCLC ...
Lei YANG, Jun-guo LU, Qing-he TAN
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2015 Significance Nonsteroidal antiinflammatory drugs (NSAIDs) work by inhibiting cyclooxygenase-2 (COX-2) induced at sites of inflammation. They are among the most widely used drugs worldwide, but their cardiovascular side effects are a major concern for ...
N. Kirkby +11 more
semanticscholar +1 more source
COX-2 “Cyclooxygenase 2“as a Prognostic marker in Breast Cancer
SVU - International Journal of Medical Sciences, 2021 Background: Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death among women in both developed and developing countries.
Fatma Zakaria Abdel-rahman +4 more
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Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine
Circulation, 2015 Background— Cardiovascular side effects associated with cyclooxygenase-2 inhibitor drugs dominate clinical concern. Cyclooxygenase-2 is expressed in the renal medulla where inhibition causes fluid retention and increased blood pressure.
B. Ahmetaj-Shala +13 more
semanticscholar +1 more source
Frontiers in Immunology, 2017 ObjectiveMultiple solid cancers contain tertiary lymphoid organs (TLO). However, it is unclear whether they promote tumor rejection, facilitate tumor evasion, or simply whether they are a byproduct of chronic inflammation.
María de la Luz García-Hernández +7 more
doaj +1 more source
Biomolecules, 2022 Inflammation and apoptosis are regulated by similar factors, including ultraviolet B (UVB) radiation and cannabinoids, which are metabolized by cyclooxygenase-2 (COX-2) into pro-apoptotic prostaglandin derivatives.
Piotr Wójcik +4 more
doaj +1 more source
Twisted Quantum Affine Superalgebra $U_q[sl(2|2)^{(2)}]$, $U_q[osp(2|2)]$ Invariant R-matrices and a New Integrable Electronic Model [PDF]
, 1996 We describe the twisted affine superalgebra $sl(2|2)^{(2)}$ and its quantized version $U_q[sl(2|2)^{(2)}]$. We investigate the tensor product representation of the 4-dimensional grade star representation for the fixed point subsuperalgebra $U_q[osp(2|2)]$.
arxiv +1 more source
Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential.
Proceedings of the National Academy of Sciences of the United States of America, 1997 Recent epidemiologic studies have shown a 40-50% reduction in mortality from colorectal cancer in individuals who take nonsteroidal antiinflammatory drugs on a regular basis compared with those not taking these agents. One property shared by all of these
M. Tsujii, S. Kawano, R. Dubois
semanticscholar +1 more source
Expression of cyclooxygenase-1 and 2 in chronic tonsillitis
Indian Journal of Pathology and Microbiology, 2010 Objectives: Prostaglandins are critical mediators of inflammation and affect both humoral and cell-mediated immune responses. Recent findings show that T and B cells express COX-2 upon activation. The purpose of this study is to investigate the potential
Dilek Fatma +4 more
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