Results 21 to 30 of about 53,400 (215)
Genome-Wide Analysis of Cyclophilin Proteins in 21 Oomycetes
Pathogens, 2019 Cyclophilins (CYPs), a highly-conserved family of proteins, belong to a subgroup of immunophilins. Ubiquitous in eukaryotes and prokaryotes, CYPs have peptidyl-prolyl cis−trans isomerase (PPIase) activity and have been implicated as virulence ...
Yan Zhang +4 more
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BMC Genomics, 2022 Background Cyclophilin (CYP) belongs to the immunophilin family and has peptidyl-prolyl cis-trans isomerase (PPIase) activity, which catalyzes the cis-trans isomerization process of proline residues.
Zhi-Wen Qiao +4 more
doaj +1 more source
Biomolecules, 2021 α,β-unsaturated carbonyls interfere with numerous plant physiological processes. One mechanism of action is their reactivity toward thiols of metabolites like cysteine and glutathione (GSH).
Daniel Maynard +9 more
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Identification of a non-mammalian leptin-like gene:characterization and expression in the tiger salamander (Ambystoma tigrinum) [PDF]
, 2006 Leptin is well established as a multifunctional cytokine in mammals. However, little is known about the evolution of the leptin gene in other vertebrates. A recently published set of ESTs from the tiger salamander (Ambystoma tigrinum) contains a sequence
Boswell, Timothy +5 more
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Suppression of Coronavirus Replication by Cyclophilin Inhibitors
Viruses, 2013 Coronaviruses infect a variety of mammalian and avian species and cause serious diseases in humans, cats, mice, and birds in the form of severe acute respiratory syndrome (SARS), feline infectious peritonitis (FIP), mouse hepatitis, and avian infectious ...
Takashi Sasaki +2 more
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FASEB BioAdvances, 2021 Macrophage apoptosis is a key contributor to the progression of atherosclerosis. Cyclophilin A, a monocyte secretory protein associated with the initiation of atherosclerosis has an inherent nuclease activity.
Vinitha Anandan +7 more
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Functional Analysis of the Lupinus luteus Cyclophilin Gene Promoter Region in Lotus japonicus
Agriculture, 2021 Functional analysis of promoter sequences is important to understand the regulation of gene expression. This study aimed to investigate the promoter region of the Lupinus luteus cytoplasmic cyclophilin gene (LlCyP; AF178458). After bioinformatic analysis,
Katarzyna Nuc +3 more
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Alternative cell death pathways and cell metabolism [PDF]
, 2013 While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells.
Fulda, Simone
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Journal of Fungi, 2022 Calcineurin (CN) is an attractive antifungal target as it is critical for growth, stress response, drug resistance, and virulence in fungal pathogens.
Praveen R. Juvvadi +4 more
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Structural and biochemical insights of CypA and AIF interaction [PDF]
, 2017 The Cyclophilin A (CypA)/Apoptosis Inducing Factor (AIF) complex is implicated in the DNA degradation in response to various cellular stress conditions, such as oxidative stress, cerebral hypoxia-ischemia and traumatic brain injury.
Caporale, Andrea +10 more
core +1 more source