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Cyclophilin B Binding to Platelets Supports Calcium-Dependent Adhesion to Collagen
Blood, 1999We have recently reported that cyclophilin B (CyPB), a secreted cyclosporine-binding protein, could bind to T lymphocytes through interactions with two types of binding sites. The first ones, referred to as type I, involve interactions with the conserved domain of CyPB and promote the endocytosis of surface-bound ligand, while the second type of ...
F, Allain +4 more
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Evidence that human milk isolated cyclophilin B corresponds to a truncated form
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1996Cyclophilin B (CyPB) is a member of the cyclophilin family (cyclosporin A-binding proteins) with specific N- and C-terminal extensions. In contrast to cyclophilin A, CyPB owns a signal sequence leading to its translocation in the endoplasmic reticulum. CyPB was reported to be present in human blood and milk, suggesting it is secreted. For this purpose,
C, Mariller +3 more
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Calcium signalling in T cells stimulated by a cyclophilin B-binding protein
Nature, 1994The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin, cyclosporin A binds and inactivates the key signalling intermediate calcineurin. To identify potential cellular homologues of cyclosporin A that might regulate calcium signalling,
R J, Bram, G R, Crabtree
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Osteogenesis Imperfecta, Normal Collagen Folding, and Lack of Cyclophilin B
New England Journal of Medicine, 2010van Dijk, F.S., Cobben, J.M., Pals, G.
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Recessive osteogenesis imperfecta and cyclophilin B
Nature Reviews Endocrinology, 2010openaire +1 more source
Inorganic Polyphosphate Influences Cyclophilin B-Mediated Protein Folding In Osteoblasts
2017Poster Presentation: no ...
Pavlov, E +5 more
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The Role of Cyclophilin B in Hepatocellular Carcinoma Development
Free Radical Biology and Medicine, 2010Yeonghwan Kim, Sung Soo Kim
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