Results 41 to 50 of about 10,795 (199)

Severe exacerbation of psoriasis after cessation of methotrexate therapy successfully treated with cyclosporin A

open access: yes, 2017
Introduction . It is estimated that erythroderma affects about 1–2% of patients with psoriasis. Objective . To present a case of psoriatic erythroderma, which was effectively treated with cyclosporin A. Case report .
Adam Reich   +3 more
core   +1 more source

What to do when traditional rescue therapies fail in acute severe ulcerative colitis [PDF]

open access: yesIntestinal Research
Acute severe ulcerative colitis (ASUC) is a medical emergency that affects approximately 25% of patients with ulcerative colitis at some point in time in their lives. Outcomes of ASUC are highly variable.
Christopher F. D. Li Wai Suen   +2 more
doaj   +1 more source

SEVERE FORM OF ATOPIC DERMATITIS AS A THERAPEUTIC CHALLENGE

open access: yesSlovenska pediatrija, 2022
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease of childhood. The disease is characterized by recurrent eczematoid itchy skin lesions caused by a combination of genetic predisposition and environmental factors (1-2).
Janja Golobič, Gašper Markelj
doaj   +1 more source

Cyclosporin-responsive enteropathy and protracted diarrhea

open access: yes, 1990
We describe a child born to unrelated parents who developed severe protracted secretory type diarrhea associated with subtotal villus atrophy and intestinal inflammation at the age of 19 months.
Searle, J.   +6 more
core   +1 more source

Increased susceptibility of striatal mitochondria to calcium-induced permeability transition

open access: yes, 2003
Mitochondria were simultaneously isolated from striatum and cortex of adult rats and compared in functional assays for their sensitivity to calcium activation of the permeability transition.
Brustovetsky, T   +11 more
core   +1 more source

Cyclosporin, Tacrolimus, Mycophenolic Acid, and Dexamethasone Suppress Peripheral Blood Mononuclear Cell Proliferation and Inhibit Interferon-Gamma, IL-10 and IL-13 Production In Vitro

open access: yesTurkish Journal of Immunology
Objective: The primary goals of immunosuppressive therapy are to prevent graft rejection and to improve graft and patient survival. Long-term maintenance therapy after kidney transplantation includes cyclosporine A (CsA), tacrolimus (FK506), mycophenolic
Abdel-Rahman Youssef
doaj   +1 more source

Calcineurin Inhibitors and Uric Acid Control in Solid Organ Transplantation: A Systematic Review

open access: yesMedical Sciences
Background/Objectives: Asymptomatic hyperuricemia has been associated with increased cardiovascular risk; it is related to factors such as diet, genetic predisposition, and drug-related side effects.
Francesca K. Martino   +6 more
doaj   +1 more source

Therapies for Chronic Spontaneous Urticaria: Present and Future Developments

open access: yesPharmaceuticals
Chronic spontaneous urticaria (CSU) is a complex dermatological condition characterized by recurrent wheals and/or angioedema lasting for more than six weeks, significantly impairing patients’ quality of life.
Riccardo Asero   +3 more
doaj   +1 more source

Lethal and Sublethal Toxicity Assessment of Cyclosporin C (a Fungal Toxin) against Plutella xylostella (L.)

open access: yesToxins, 2022
Secondary metabolites/toxins produced by Purpeocillium lilacinum (Hypocreales; Phiocordycipitaceae), a well-known insect pathogen, can be used for the management of different insect pests.
Jianhui Wu   +3 more
doaj   +1 more source

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy