Results 61 to 70 of about 10,795 (199)
Asia-Pacific Journal of Clinical Oncology, EarlyView.We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija +6 more
wiley +1 more source
Drug Target Insights, 2007 Cyclophilin (CyP) is a peptidyl prolyl cis/trans isomerase, catalyzing the cis-trans isomerization of proline residues in proteins. CyP plays key roles in several different aspects of cellular physiology including the immune response, transcription ...
Koichi Watashi, Kunitada Shimotohno
doaj
Absorption kinetics of cyclosporin in the rat
, 1992 Cyclosporin was administered (6 mg kg−1, i.v.) over 15 min, or (10 mg kg−1) by gavage, to two groups of 5 rats. Following i.v. infusion, cyclosporin exhibited triphasic behaviour with mean ± s.e.m. disposition half-lives of 9·0 ± 1·3 min, 4·0 ± 0·5 h and
Malcolm Rowland +2 more
core +1 more source
Australasian Journal of Dermatology, EarlyView.ABSTRACT Background/Objectives Dupilumab is an anti‐interleukin (IL)‐4 receptor (IL‐4Rα) monoclonal antibody used to manage atopic dermatitis (AD). There is a paucity of real‐world Australian data for dupilumab in paediatric AD, especially regarding differences in clinical profiles between age groups.
Paul Sun Woo Kim +7 more
wiley +1 more source
Cyclosporin A in psoriasis [PDF]
, 1991 Although a large therapeutic arsenal of conventional drugs is available to treat patients with psoriasis, a group of patients still exists that fulfill the inherent exclusion criteria or present with subjective or objective side-effects.
Heule, F. (Freerk)
core
Cyclophilins as Modulators of Viral Replication
Viruses, 2013 Cyclophilins are peptidyl‐prolyl cis/trans isomerases important in the proper folding of certain proteins. Mounting evidence supports varied roles of cyclophilins, either positive or negative, in the life cycles of diverse viruses, but the nature and ...
Stephen D. Frausto +2 more
doaj +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary This second part of the S3 guideline on the diagnosis and treatment of alopecia areata (AA), presents key recommendations on topical and systemic therapy, quality of life and support services. The first part of the guideline, published separately, covers the definition and content of epidemiology and diagnosis as well as comorbidities, risk and
Ulrike Blume‐Peytavi +13 more
wiley +1 more source
Stevens-Johnson Syndrome and Its Manifestation in Oral Cavity
Česká Stomatologie a Praktické Zubní Lékařství, 2010 Stevens-Johnson syndrome (SJS) is a disease with typical dermal and mucosal manifestations. The etiology is multifactorial. The characteristic skin manifestation is the occurrence of brick-red stains or papular dermatitis with central decrease, sc.
J. Vokurka +5 more
doaj +1 more source
Diltiazem-cyclosporin pharmacokinetic interaction - dose-response relationship.
, 1997 Aims: To study the dose-response relationship of the pharmacokinetic interaction between diltiazem and cyclosporin in kidney transplant recipients. Methods: Eight stable kidney transplant recipients maintained on cyclosporin but not taking diltiazem ...
Mathew, T., Morris, R., Jones, T.
core +1 more source
Internal Medicine Journal, EarlyView.Abstract Background Advances in haemopoietic stem cell transplantation (HSCT) have improved long‐term survival, but they have also led to late complications, such as nephropathy. However, the safety and feasibility of kidney transplantation (KT) in patients with HSCT‐related end‐stage kidney disease (ESKD) remain unclear.
Bioh Kim +6 more
wiley +1 more source