Results 61 to 70 of about 80,641 (196)

Efficiency of cyclosporin A therapy in patients with myelodysplastic syndrome

Терапевтический архив, 2010
Aim. To evaluate the efficacy of cyclosporin A (CsA) in patients with myelodysplastic syndromes (MDS) and to identify determinants of a response to this therapy. Subjects and methods.
A V Kokhno, E N Parovichnikova, E A Mikhailova, E N Ustinova, I B Kaplanskaya, V N Dvirnyk, Yu V Olshanskaya, E V Domracheva, V G Savchenko   +8 more
doaj  

Screening of fungal metabolites in Brazil nuts using LC/MS/MS [PDF]

, 2010
The aim of this study was to evaluate quantitatively the occurrence of fungal metabolites in Brazil nuts. Nuts were collected from Agroforest production areas in Amazon basin region.
Silva, Otniel Freitas, Souza, Maria de Lourdes M., Venâncio, Armando   +2 more
core  

Possible mechanisms involved in the protective effect of lutein against cyclosporine-induced testicular damage in rats

Heliyon
Oxidative stress and aberrant inflammatory response have important implications in cyclosporin-induced reproductive functions. Previous studies have shown that agents with antioxidant and anti-inflammatory activities might be beneficial in reversing ...
Obukohwo Mega Oyovwi, Benneth Ben-Azu, Edesiri Prince Tesi, Victor Emojevwe, Rume Arientare Rotu, Goodies Emuesiri Moke, Emuesiri Umukoro, Jerome Ndudi Asiwe, Kingsley Eze Nwangwa   +8 more
doaj   +1 more source

The use of FK-506 for small intestine llotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease [PDF]

, 1990
Small intestine allotransplantation in humans is not yet feasible due to the failure of the current methods of immunosuppression. FK-506, a powerful new immunosuppressive agent that is synergistic with cyclosporine, allows long-term survival of ...
Banner, B, Cai, X, Cramer, DV, Hoffman, AL, Makowka, L, Pascualone, A, Starzl, TE, Todo, S   +7 more
core   +1 more source

Cyclosporin A inhibits PGE2 release from vascular smooth muscle cells [PDF]

, 1987
The influence of the fungoid undecapeptide cyclosporin A (CyA) on PGE2 release from cultured rat aortic smooth muscle cells was investigated in this study.
Koch, K. M., Kurtz, Armin, Kühn, K., Pfeilschifter, J.   +3 more
core   +1 more source

Severe exacerbation of psoriasis after cessation of methotrexate therapy successfully treated with cyclosporin A

Przegląd Dermatologiczny, 2017
Introduction . It is estimated that erythroderma affects about 1–2% of patients with psoriasis. Objective . To present a case of psoriatic erythroderma, which was effectively treated with cyclosporin A. Case report .
Aleksandra Bartczyszyn-Kmiecik, Magdalena Żychowska, Radomir Reszke, Adam Reich   +3 more
doaj   +1 more source

Efficacy of hepatic transplantation in patients with primary sclerosing cholangitis [PDF]

, 1993
Controlled trials to assess the therapeutic benefit of orthotopic hepatic transplantation (OHTx) for primary sclerosing cholangitis (PSC) cannot be justified in view of improvement of patient survival after this operation since 1981.
Abu-Elmagd, KM, Demetris, AJ, Dickson, ER, Fung, JJ, Krom, RAF, Langworthy, AL, Malinchoc, M, Murtaugh, PA, Starzl, TE, Van Thiel, DH   +9 more
core  

Pathologic analysis of liver transplantation for primary biliary cirrhosis [PDF]

, 1988
A retrospective histopathologic review of all pathologic specimens from 394 adult liver transplant patients was undertaken with clinical correlation to determine if primary biliary cirrhosis has affected the posttrans‐plant course compared to all other ...
Ballardini, Baum, Berg, Bernuau, Demetris, Demetris, Demetris, Demetris, Detre, Epstein, Epstein, Esquivel, Fennell, Fung, Haagsma, Iwatsuki, James, MacSween, McFarlane, McFarlane, Neuberger, Popper, Portmann, Portmann, Portmann, Vento   +25 more
core   +1 more source

Cyclosporin A Reverses Chemoresistance in Patients With Gynecologic Malignancies

Neoplasia: An International Journal for Oncology Research, 1999
Multidrug resistance is a major obstacle in successful systemic therapy of gynecologic malignancies. The objectives of this study are to evaluate the activity of cyclosporin A used to overcome drug resistance in a variety of gynecologic malignancies ...
Anil K. Sood, Joel I. Sorosky, Robert C. Squatrito, Jeffrey S. Skilling, Barrie Anderson, Richard E. Buller   +5 more
doaj   +1 more source

Deferasirox Targeting Ferroptosis Synergistically Ameliorates Myocardial Ischemia Reperfusion Injury in Conjunction With Cyclosporine A

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Ferroptosis, an iron‐dependent form of regulated cell death, is a major cell death mode in myocardial ischemia reperfusion (I/R) injury, along with mitochondrial permeability transition‐driven necrosis, which is inhibited by cyclosporine A ...
Kosei Ishimaru, Masataka Ikeda, Hiroko Deguchi Miyamoto, Shun Furusawa, Ko Abe, Masatsugu Watanabe, Takuya Kanamura, Satoshi Fujita, Ryohei Nishimura, Takayuki Toyohara, Shouji Matsushima, Tomoko Koumura, Ken‐ichi Yamada, Hirotaka Imai, Hiroyuki Tsutsui, Tomomi Ide   +15 more
doaj   +1 more source