Results 21 to 30 of about 126,219 (197)

Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood-pressure independent effect [PDF]

open access: yes, 2016
Compound 21 (C21), selective agonist of AT2 receptors, shows antinflammatory effects in hypertension and nephroprotection in diabetes. The aim of this study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized mainly by ...
Carletti, R   +5 more
core   +1 more source

Cyclosporine augments hepatic regenerative response in rats [PDF]

open access: yes, 1990
A number of mechanisms participate in the hepatic injury that occurs during and following liver transplantation. A normal allograft regenerative response is probably essential for a successful transplant outcome. In this study, the effect of cyclosporine,
Dindzans, V   +6 more
core   +1 more source

The use of FK-506 for small intestine llotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease [PDF]

open access: yes, 1990
Small intestine allotransplantation in humans is not yet feasible due to the failure of the current methods of immunosuppression. FK-506, a powerful new immunosuppressive agent that is synergistic with cyclosporine, allows long-term survival of ...
Banner, B   +7 more
core   +1 more source

Cyclosporine A to Treat Unexplained Recurrent Spontaneous Abortions: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Single-Center Trial

open access: yesInternational Journal of Women's Health, 2021
Nan Wang,1,2 Hongshan Ge,1 Shu Zhou1 1Department of Obstetrics and Gynecology, Taizhou People’s Hospital, Taizhou, Jiangsu Province, People’s Republic of China; 2Department of Graduate College, Dalian Medical University, Dalian, Liaoning Province, People’
Wang N, Ge H, Zhou S
doaj  

Tolerogenic vaccine composited with islet-derived multipeptides and cyclosporin A induces pTreg and prevents Type 1 diabetes in murine model

open access: yesHuman Vaccines & Immunotherapeutics, 2020
Regulatory T cells (Tregs) play a crucial role in the control of the initiation and progression of type 1 diabetes (T1D). Various immunological interventions including those to ex vivo expansion Tregs transfer, in vivo induction of peripherally derived ...
Xian Zhou   +7 more
doaj   +1 more source

The Cyclosporine-A Treatment does not have Harmful Effect on the Linear Growth of Pediatric Patients with Steroid-dependent and Steroid-resistant Nephrotic Syndrome [PDF]

open access: yesChildhood Kidney Diseases, 2016
Purpose This study was performed to evaluate the effects of cyclosporine-A (CsA) on linear growth in pediatric patients with steroid-dependent (SDNS) or resistant nephrotic syndrome (SRNS).
Sang Soo Lee   +6 more
doaj   +1 more source

The changes of mitochondrial cytochrome c and GABAergic neuron in neuropathic pain model [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
BackgroundRole of cytochrome c (Cyt c) is an apoptogenic agent under certain conditions. The mitochondrial permeability transition pore (MPTP) plays an important role in cell death since it opens, leading to mitochondrial swelling and release of Cyt c ...
Won Sung Kim   +3 more
doaj   +1 more source

An investigation of the effectiveness of oral cyclosporine on perioperative myocardial injury (PMI) in patients who undergo the surgical procedure of coronary artery bypass graft (CABG): A Randomized Controlled Clinical Trial

open access: yesJournal of Family Medicine and Primary Care, 2021
Background: Routine clinical strategies for the prevention of myocardial infarction (MI) during the surgical procedure of CABG include cross-clamp fibrillation and cardioplegia have failed to decrease the risk of perioperative myocardial injury (PMI ...
Seyed Mohammad Hassan Adel   +2 more
doaj   +1 more source

Nano-selenium supplementation upregulate TLR-7, MyD88, NF-kB, and TRAF6 genes in thymus of Wistar rats following treatment with cyclosporine A [PDF]

open access: yesNanomedicine Journal
Objective(s): Selenium Nanoparticles can modulate the function of the immune system and improve immunity. We investigate the expression of toll-like receptor-7 (TLR-7), myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa B (NF-κB ...
Nafiseh Rezvani   +2 more
doaj   +1 more source

In vitro Characterization and Release Studies of Combined Nonionic Surfactant-Based Vesicles for the Prolonged Delivery of an Immunosuppressant Model Drug

open access: yesInternational Journal of Nanomedicine, 2020
Akhtar Rasul,1,* Muhammad Imran Khan,2,* Mujeeb Ur Rehman,1,* Ghulam Abbas,1,* Nosheen Aslam,3,* Shabbir Ahmad,4,* Khizar Abbas,5,* Pervaiz Akhtar Shah,6,* Muhammad Iqbal,7,* Ali Mohammad Ahmed Al Subari,6,* Talal Shaheer,8,* Shahid Shah9,* 1Department ...
Rasul A   +11 more
doaj  

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