Results 101 to 110 of about 2,768 (247)

Tolypocladamides A-G: Cytotoxic Peptaibols from <i>Tolypocladium inflatum</i>. [PDF]

open access: yesJ Nat Prod, 2022
Senadeera SPD   +11 more
europepmc   +1 more source

Loss of Response to Anti‐Tumor Necrosis Factor Alpha Therapy in Patients With Inflammatory Bowel Disease: A Real‐World Comparison of Combination Therapy Versus Monotherapy

open access: yesJGH Open, Volume 10, Issue 3, March 2026.
ABSTRACT Objectives The success of anti‐TNFα agents has changed the landscape of treatment for inflammatory bowel diseases (IBD). One major limitation to this success is the secondary loss of response (sLOR) phenomenon. Combination therapy with immunomodulating agents has been shown to be effective in reducing the sLOR process.
Faris Chater   +6 more
wiley   +1 more source

Mechanosensitive Ion Channel PIEZO1 Suppresses BMP2‐Induced Ossification of the Annulus Fibrosus Cells

open access: yesJOR SPINE, Volume 9, Issue 1, March 2026.
This study aimed to elucidate the function of PIEZO1in AF cells under mechanical stimulation. Low‐magnitude cyclictensile strain (CTS, 2%) suppressed osteogenic marker expression. Pharmacological activation of PIEZO1 using Yoda1 mimics the effects oflow‐strain CTS.
Hisakazu Shitozawa   +9 more
wiley   +1 more source

Delayed Time to First Skin Cancer Among Hematopoietic Stem Cell Transplant Recipients With Chronic Cutaneous Graft‐Versus‐Host Disease

open access: yesJEADV Clinical Practice, Volume 5, Issue 1, Page 201-204, March 2026.
ABSTRACT Background Hematopoietic stem cell transplant (HSCT) recipients face an increased risk of cutaneous malignancies. Chronic cutaneous graft‐versus‐host disease (cGVHD), specific to allogeneic HSCT (alloHSCT), has been proposed to further elevate this risk, though its impact on skin cancer latency and distribution remains unclear.
Amy J. Petty   +2 more
wiley   +1 more source

Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat

open access: yesJEADV Clinical Practice, Volume 5, Issue 1, Page 250-253, March 2026.
Capsule summary Mpox is a zoonotic infection that may present severe dissemination in patients with pre‐existing dermatoses. We report a 30‐year‐old man with active atopic dermatitis who developed extensive, sexually transmitted mpox with widespread cutaneous involvement consistent with eczema monkeypoxicum.
Andrés Vidal González   +6 more
wiley   +1 more source

Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species

open access: yesPLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana   +4 more
wiley   +1 more source

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides

open access: yesJournal of Peptide Science, Volume 32, Issue 3, March 2026.
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama   +2 more
wiley   +1 more source

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