Results 41 to 50 of about 3,781 (190)

A Strong Neutrophil Elastase Proteolytic Fingerprint Marks the Carcinoma Tumor Proteome [PDF]

, 2016
Proteolytic cascades are deeply involved in critical stages of cancer progression. During the course of peptide-wise analysis of shotgun proteomic data sets representative of colon adenocarcinoma (AC) and ulcerative colitis (UC), we detected a cancer-
Dadlez, Michal, Dębski, Janusz, Karczmarski, Jakub, Kistowski, Michal, Mikula, Michał, Olędzki, Jacek, Ostrowski, Jerzy, Paziewska, Agnieszka   +7 more
core   +1 more source

Disease map-based biomarker selection and pre-validation for bladder cancer diagnostic [PDF]

, 2015
YesContext: Urinary biomarkers are promising as simple alternatives to cystoscopy for the diagnosis of de novo and recurrent bladder cancer. Objective: To identify a highly sensitive and specific biomarker candidate set with potential clinical utility ...
De Paoli, M., Feng, G.J., Lukas, A., Marquette, C., Morgan, Richard, Mühlberger, I., Pandha, H.S., Perco, P.   +7 more
core   +1 more source

Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours [PDF]

, 2010
Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours Renee GHM van Sprundel1, Ted SGAM van den Ingh2, Valeer J Desmet3, Azeam Katoonizadeh3, Louis C Penning1, Jan Rothuizen1, Tania Roskams3 and ...
Desmet, V.J., Katoonizadeh, A., Penning, L.C., Roskams, T., Rothuizen, J., Spee, B., Sprundel, R.G., van den Ingh, T.S.G.A.M.   +7 more
core   +3 more sources

ANGER IN CHILDREN: A MINIREVIEW [PDF]

, 2017
Aggressive behavior is a peculiar characteristic of most animal species playing an important role in species preservation and two types have been identified: interspecific and intraspecific aggression.
D\u2019Oro, L., Gallai, B., Lavano, R., Lavano, S., Maltese, A., Marotta, R., Romano, P., Salerno, M., Tripi, G.   +8 more
core   +1 more source

Clinical characteristics, treatment response, and survival outcomes in melanoma patients with cavity carcinomatosis: A retrospective analysis

International Journal of Cancer, EarlyView.
What's New? Cavity carcinomatosis, a late manifestation of cancer, fuels tumor formation throughout a large area, most commonly the peritoneal and pleural cavities. The condition also can lead to resistance to otherwise effective treatment strategies.
Zhongqiao Lin, Li Zhu, Yuyang Huang, Lizhu Chen, Yuping Lu, Yu Chen, Jing Lin   +6 more
wiley   +1 more source

Pleural Fluid Mesothelin as an Adjunct to the Diagnosis of Pleural Malignant Mesothelioma [PDF]

, 2014
Rationale:. The diagnosis of pleural malignant mesothelioma (MM) by effusion cytology may be difficult and is currently controversial. Effusion mesothelin levels are increased in patients with MM but the clinical role of this test is uncertain ...
Creaney, Jenette, Dick, Ian M., Musk, A. W(Bill), Olsen, Nola, Robinson, Bruce W., Segal, Amanda, Skates, Steven J.   +6 more
core   +2 more sources

Clinical Significance of Serum Assay of CYFRA21-1 in Primary Lung Cancer.

Haigan, 1995
原発性肺癌における新しい腫瘍マーカーであるサイトケラチン19フラグメント (CYFRA21-1) の臨床的意義を検討するため原発性肺癌患者52例と他の肺疾患患者38例, 健常者22例について血清CYFRA21-1を測定し, 他の腫瘍マ-カー (CEA, SCC, NSE) と比較検討した.cut-off値を3.5ng/mlとすると原発性肺癌における陽性率は65%, 他の肺疾患における偽陽性率は8%であった.組織型別では, 扁平上皮癌で88.9%と最も高い陽性率を示し, 腺癌でも61.5%の陽性率を示した.免疫組織学的検討では扁平上皮癌において細胞質内で均一に強陽性に染色された.臨床病期別検討では, 1期50%, II期50%, IIIA期40%, IIIB期71%, IV期72 ...
Takahiko Horiguchi, Souichi Tachikawa, Eiji Munekata, Noriyuki Takeuchi, Kouichi Hirabuki, Mamoru Shiga, Masahiro Sugiyama, Rieko Kondou, Junichi Miyazaki, Misuzu Handa   +9 more
openaire   +2 more sources

Integrating Clinical Features, Laboratory Biomarkers and Computed Tomography for the Discrimination of Non‐Small Cell Lung Cancer and Benign Pulmonary Diseases: A Clinical Prediction Model

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed and validated a clinical prediction model to differentiate non‐small cell lung cancer (NSCLC) from benign pulmonary diseases using clinical features, laboratory biomarkers, and CT features. The model achieved an AUC‐ROC of 0.95 in the training set and 0.82 in the validation set, demonstrating reliable diagnostic performance and ...
Jie Zhang, Shui Liu, Mingjian Bai, Fucun Ma, Guowei Liang, Bing Wang   +5 more
wiley   +1 more source

A retrospective study for prognostic significance of type II diabetes mellitus and hemoglobin A1c levels in non-small cell lung cancer patients treated with pembrolizumab [PDF]

, 2022
Background: Diabetes mellitus (DM) is common and recognized as a risk factor for developing non-small cell lung cancer (NSCLC) while the prognostic evaluation is still controversial. As immunotherapy is widely used in clinical practice, its efficacy and
Abed, Afaf, Chang, Qing, Chu, Tianqing, Gelsomino, Francesco, Kim, Yeon Wook, Lei, Yuqiong, Li, Jiaqi, Qian, Jialin, Qiang, Huiping, Shen, Yinchen, Stella, Giulia Maria, Zhong, Runbo   +11 more
core   +2 more sources

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source