Results 41 to 50 of about 3,841 (191)

A Strong Neutrophil Elastase Proteolytic Fingerprint Marks the Carcinoma Tumor Proteome [PDF]

open access: yes, 2016
Proteolytic cascades are deeply involved in critical stages of cancer progression. During the course of peptide-wise analysis of shotgun proteomic data sets representative of colon adenocarcinoma (AC) and ulcerative colitis (UC), we detected a cancer-
Dadlez, Michal   +7 more
core   +1 more source

Disease map-based biomarker selection and pre-validation for bladder cancer diagnostic [PDF]

open access: yes, 2015
YesContext: Urinary biomarkers are promising as simple alternatives to cystoscopy for the diagnosis of de novo and recurrent bladder cancer. Objective: To identify a highly sensitive and specific biomarker candidate set with potential clinical utility ...
De Paoli, M.   +7 more
core   +1 more source

Clinical characteristics, treatment response, and survival outcomes in melanoma patients with cavity carcinomatosis: A retrospective analysis

open access: yesInternational Journal of Cancer, Volume 158, Issue 9, Page 2418-2428, 1 May 2026.
What's new? Cavity carcinomatosis, a late manifestation of cancer, fuels tumor formation throughout a large area, most commonly the peritoneal and pleural cavities. The condition also can lead to resistance to otherwise effective treatment strategies.
Zhongqiao Lin   +6 more
wiley   +1 more source

Clinical meaning of age-related expression of fecal cytokeratin 19 in colorectal malignancy [PDF]

open access: yes, 2009
Background Colorectal cancer (CRC) is one of the leading causes of malignant death worldwide. Because young age of onset is often considered a poor prognostic factor for CRC, it is important to identify the poor outcomes of CRC in a younger population ...
Sun Hsiao-Lun   +11 more
core   +2 more sources

Clinical Significance of Serum Assay of CYFRA21-1 in Primary Lung Cancer.

open access: yesHaigan, 1995
原発性肺癌における新しい腫瘍マーカーであるサイトケラチン19フラグメント (CYFRA21-1) の臨床的意義を検討するため原発性肺癌患者52例と他の肺疾患患者38例, 健常者22例について血清CYFRA21-1を測定し, 他の腫瘍マ-カー (CEA, SCC, NSE) と比較検討した.cut-off値を3.5ng/mlとすると原発性肺癌における陽性率は65%, 他の肺疾患における偽陽性率は8%であった.組織型別では, 扁平上皮癌で88.9%と最も高い陽性率を示し, 腺癌でも61.5%の陽性率を示した.免疫組織学的検討では扁平上皮癌において細胞質内で均一に強陽性に染色された.臨床病期別検討では, 1期50%, II期50%, IIIA期40%, IIIB期71%, IV期72 ...
Takahiko Horiguchi   +9 more
openaire   +2 more sources

Cytopathologic Features of Metastatic Malignant Mesothelioma With SMARCB1 (INI‐1) Deficient Diagnosed by Ultrasound‐Guided Fine‐Needle Aspiration: A Case Report

open access: yesDiagnostic Cytopathology, Volume 54, Issue 4, Page E87-E92, April 2026.
ABSTRACT Malignant mesothelioma (MM) is a rare yet aggressive neoplasm that arises from mesothelial cells lining the thoracic and abdominal cavities, the pericardium, and the tunica testis. Characterized by rapid progression, high invasiveness, and a poor prognosis, MM poses significant clinical challenges. SMARCB1, also referred to as INI‐1, hSNF5, or
Jun Yang   +4 more
wiley   +1 more source

ANGER IN CHILDREN: A MINIREVIEW [PDF]

open access: yes, 2017
Aggressive behavior is a peculiar characteristic of most animal species playing an important role in species preservation and two types have been identified: interspecific and intraspecific aggression.
D\u2019Oro, L.   +8 more
core   +1 more source

Case of Gastric Signet Ring Cell Carcinoma With Pulmonary Lymphangitic Carcinomatosis as the Initial Manifestation Diagnosed by Computed Tomography‐Guided Percutaneous Lung Biopsy

open access: yesRespirology Case Reports, Volume 14, Issue 4, April 2026.
We report a case of gastric signet ring cell carcinoma with pulmonary lymphangitic carcinomatosis as the initial manifestation without gastrointestinal symptoms confirmed by CT‐guided percutaneous lung biopsy, with the aim of providing insights into diagnostic methods and differential diagnosis of similar cases.
Ping Li   +3 more
wiley   +1 more source

Pleural Fluid Mesothelin as an Adjunct to the Diagnosis of Pleural Malignant Mesothelioma [PDF]

open access: yes, 2014
Rationale:. The diagnosis of pleural malignant mesothelioma (MM) by effusion cytology may be difficult and is currently controversial. Effusion mesothelin levels are increased in patients with MM but the clinical role of this test is uncertain ...
Creaney, Jenette   +6 more
core   +2 more sources

A retrospective study for prognostic significance of type II diabetes mellitus and hemoglobin A1c levels in non-small cell lung cancer patients treated with pembrolizumab [PDF]

open access: yes, 2022
Background: Diabetes mellitus (DM) is common and recognized as a risk factor for developing non-small cell lung cancer (NSCLC) while the prognostic evaluation is still controversial. As immunotherapy is widely used in clinical practice, its efficacy and
Abed, Afaf   +11 more
core   +2 more sources

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