Results 51 to 60 of about 3,781 (190)

Test and Significance of CEA, NSE, CA125, CYFRA21-1 in Lung Cancer [PDF]

open access: yes, 2017
目的 探讨CEA、NSE、CA125、CYFRA21-1在肺癌中的检测及意义.方法 回顾性分析2015年10月—2016年12月医院收治的肺部疾病患者166例,其中89例肺癌患者设为肺癌组,其余77例肺部良性病变患者设为肺部良性病变组.另选择35名健康志愿者作为健康对照组,电化学发光法检测3组血清中CEA、NSE、CA125、CYFRA21-1含量,分析单项及联合检测对肺癌的诊断价值.结果 肺癌组患者血清CEA、NSE、CA125、CYFRA21-1分别为(4.32±0.83)ng/mL、(11.54 ...
何佳瑜, 何正, 罗世翊, 魏玲
core   +1 more source

Primary Mediastinal Malignant Melanoma Presenting With Pleural Effusion: A Case Report

open access: yesCancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Primary mediastinal malignant melanoma (PMMM) presenting with pleural effusion as the initial manifestation is exceedingly rare, presenting significant diagnostic and therapeutic challenges. This article reports a case of PMMM that initially manifested as pleural effusion and includes a review of the relevant literature.
Minlian Nong   +4 more
wiley   +1 more source

Serum CYFRA21-1 as an effective tumor biomarker for patients with nasopharyngeal carcinoma

open access: yesNeoplasma, 2015
We investigated if the serum cytokeratin 19 fragment 21.1 (CYFRA21-1) level was elevated in nasopharyngeal carcinoma (NPC) and can function as a biomarker for detection and monitoring of NPC. Three hundred and one study subjects were divided into two groups: the NPC group (n=126) and healthy control group (n=175).
X M, Song   +5 more
openaire   +3 more sources

Non‐Destructively Quantifying the Whole‐Course Growth and Drug‐Response of PDOs by an Automatic Microfluidic System Utilizing Chemiluminescence Detection

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The detection of secreted biomarkers enables molecular variations monitoring of organoid status. In this study, the non‐destructive quantification for the whole‐course growth and drug‐response of PDOs is first realized using a multifunctional microfluidic chip‐based system(ASMO) that integrates culturing, drug incubation, and biomarker detection ...
Yu Zhang   +12 more
wiley   +1 more source

Significance of Serum Tumor Markers in Esophageal and Gastric Cancers: A Systematic Literature Review

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 54-66, January 2026.
The utility of serum tumor markers in esophageal squamous cell carcinoma and gastric cancer were evaluated by systematic review and meta‐analysis. In addition, the position of each marker, strategies for improving their accuracy in the future, and new markers are also described.
Yasunori Matsumoto   +2 more
wiley   +1 more source

Aggregation‐induced emission luminogens in in vitro diagnostics: Advancing biomarker detection in body fluids

open access: yesInterdisciplinary Medicine, Volume 4, Issue 1, January 2026.
This review systematically summarizes recent advances in aggregation‐induced emission (AIE) materials for in vitro diagnostics (IVD). It highlights probe design strategies—categorizing them into direct‐responsive, indirect‐responsive, and nano‐immunoprobes—and their applications in detecting a wide range of biomarkers across diverse body fluids ...
Qi Liu   +5 more
wiley   +1 more source

Clinical Significance of Serum Cytokeratin 19 Fragment in the Prediction of Chemotherapy Efficacy and Prognosis in Patients with Advanced Non-small Cell Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2010
Background and objective RECIST (Response Evaluation Criteria in Solid Tumors) criteria could not be used to detect viable tumor tissue and is not an accurate tool for evaluation of objective response (OR) in non-small cell lung cancer (NSCLC) patients ...
Chong'an XU   +3 more
doaj  

Cyfra 21-1 as a serum tumor marker for follow up of patients with laryngeal and hypopharyngeal squamous cell carcinoma [PDF]

open access: yes, 2009
AIM: To evaluate the importance and potential of Cyfra21-1 as a tumor marker (TM) for follow-up of patients with squamous cell carcinoma (SCC) in laryngeal and hypopharyngeal cancer.
Al-Shagahin, Hani
core   +1 more source

Nanotechnology‐Enhanced Approaches for Early Cancer Diagnosis

open access: yesNano Select, Volume 7, Issue 1, January 2026.
Conventional MRI and PET provide limited sensitivity and contrast for precise brain lesion detection. In contrast, radiolabeled nanoparticlebased PET imaging enables enhanced signal specificity and sensitivity. By integrating multifunctional nanoprobes, this platform improves multimodal imaging performance, allowing more accurate visualization of ...
Jongmoo Lee   +5 more
wiley   +1 more source

Potential Diagnosis and Prognosis Value of Plasma MicroRNA-19a in Esophageal Cancer [PDF]

open access: yes, 2015
背景:食管癌是发生于食管上皮组织的恶性肿瘤,具有高死亡率、高复发率和高转移率的特点。然而目前针对食管癌敏感的肿瘤标志物不多,且诊断效率较低,远远不能满足临床需求。MicroRNA是一类非编码RNA,可以稳定存在于人体血浆中并且易于检测。据报道,microRNA在诸多疾病状态下会出现表达异常,如食管癌、结直肠癌、肝癌等,这一发现极大地增加了血浆microRNA作为食管癌标志物的可能。在前期实验中,我们观察到microRNA-19a(miR-19a)在食管癌血浆标本中高表达,本文将重点探讨miR ...
白永颖
core  

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