Results 51 to 60 of about 3,841 (191)
Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT This case report describes a 75‐year‐old male patient who was admitted due to acute intestinal obstruction. The patient had a history of small cell lung cancer. Emergency surgery pathology confirmed the presence of primary composite small cell lung cancer with rare independent dual component metastasis: The colonic lesion was metastatic poorly
Wei Jiang, Xiaohui Zhou, Xizhang Zhu
wiley +1 more source
Serum CYFRA21-1 as an effective tumor biomarker for patients with nasopharyngeal carcinoma
Neoplasma, 2015 We investigated if the serum cytokeratin 19 fragment 21.1 (CYFRA21-1) level was elevated in nasopharyngeal carcinoma (NPC) and can function as a biomarker for detection and monitoring of NPC. Three hundred and one study subjects were divided into two groups: the NPC group (n=126) and healthy control group (n=175).
X M, Song +5 more
openaire +3 more sources
Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.ABSTRACT Early detection of oesophageal squamous cell carcinoma (ESCC) is critical for improving survival, yet current screening is hampered by the lack of effective, non‐invasive methods. Here, we developed and prospectively validated an extracellular vesicle (EV) protein‐based blood test for the preclinical detection of ESCC.
Yu Wang +23 more
wiley +1 more source
Early Cancer Detection: What's Going on and What's Next
MedComm, Volume 7, Issue 3, March 2026.Multicancer early detection (MCED) platforms have emerged as a promising strategy for the safe and effective early detection of multiple cancer types, with the potential to reduce metastatic burden and improve clinical outcomes, particularly for aggressive malignancies that lack effective population‐level screening.
Emma Di Carlo
wiley +1 more source
Test and Significance of CEA, NSE, CA125, CYFRA21-1 in Lung Cancer [PDF]
, 2017 目的 探讨CEA、NSE、CA125、CYFRA21-1在肺癌中的检测及意义.方法 回顾性分析2015年10月—2016年12月医院收治的肺部疾病患者166例,其中89例肺癌患者设为肺癌组,其余77例肺部良性病变患者设为肺部良性病变组.另选择35名健康志愿者作为健康对照组,电化学发光法检测3组血清中CEA、NSE、CA125、CYFRA21-1含量,分析单项及联合检测对肺癌的诊断价值.结果 肺癌组患者血清CEA、NSE、CA125、CYFRA21-1分别为（4.32±0.83）ng/mL、（11.54 ...
何佳瑜, 何正, 罗世翊, 魏玲
core +1 more source
Clinical and Translational Science, Volume 19, Issue 3, March 2026.ABSTRACT Circulating serum biomarkers have prognostic value in patients with advanced NSCLC, yet their potential still remains underappreciated at present. This review discusses classical approaches of biomarker data analysis, highlighting gaps, and summarizing current methodologies to evaluate the relationship between serum biomarkers and clinical ...
Francis Williams Ojara +6 more
wiley +1 more source
Chinese Journal of Lung Cancer, 2010 Background and objective RECIST (Response Evaluation Criteria in Solid Tumors) criteria could not be used to detect viable tumor tissue and is not an accurate tool for evaluation of objective response (OR) in non-small cell lung cancer (NSCLC) patients ...
Chong'an XU +3 more
doaj
Development of an enzyme-linked immunosorbent assay for the detection of human calretinin in plasma and serum of mesothelioma patients [PDF]
, 2010 Background Calretinin is one of the well-established immunohistochemical markers in the diagnostics of malignant mesothelioma (MM). Its utility as a diagnostic tool in human blood, however, is scarcely investigated.
Irina Raiko +33 more
core +1 more source
Cancer Medicine, Volume 15, Issue 2, February 2026.ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley +1 more source
Primary Mediastinal Malignant Melanoma Presenting With Pleural Effusion: A Case Report
Cancer Reports, Volume 9, Issue 2, February 2026.ABSTRACT Background Primary mediastinal malignant melanoma (PMMM) presenting with pleural effusion as the initial manifestation is exceedingly rare, presenting significant diagnostic and therapeutic challenges. This article reports a case of PMMM that initially manifested as pleural effusion and includes a review of the relevant literature.
Minlian Nong +4 more
wiley +1 more source