Results 121 to 130 of about 10,726 (197)

The involvement of miRNAs in CYP450 enzymes and UDP-glucuronosyltransferases regulation in the human liver. [PDF]

Sci Rep
Szeląg-Pieniek S, Perużyńska M, Komaniecka N, Kurzawski M, Oswald S, Łapczuk-Romańska J, Droździk M.   +6 more
europepmc   +1 more source

Research progress on the pathophysiological mechanisms of pioglitazone-induced heart failure: a review. [PDF]

Front Cardiovasc Med
Li J, Zhang Y, Li X.
europepmc   +1 more source

Six-compound cocktail for maturation of human pluripotent stem cell-derived liver spheroids for toxicity prediction. [PDF]

Nat Commun
Tian L, Anas FH, Hasselkus R, Joseph E, Chadraa M, Koç B, Wu W, Karnam B, Flores-Muñoz P, Alon A, Morris J, Bentwich I, Bein A.   +12 more
europepmc   +1 more source

HBV-induced miR-4461 downregulation correlates with elevated fibrinogen alpha chain expression in hepatocellular carcinoma. [PDF]

J Gastroenterol
Kanai M, Sakai A, Date T, Aoki Y, Mihara F, Kokudo T, Inagaki F, Takemura N, Kokudo N, Sugiyama M.   +9 more
europepmc   +1 more source

Interindividual variability in imatinib metabolism in human liver microsomes and primary human hepatocytes: Impact of CYP2C8 and CYP3A phenotypes. [PDF]

Drug Metab Dispos
Latham BD, Montazeri P, Lanphier RM, Gerringer AJ, Interrante T, Jones CD, De Busysscher T, Fallon JK, Jackson KD.   +8 more
europepmc   +1 more source

Mechanistic Physiologically Based Pharmacokinetic Modeling to Predict CYP3A4-Mediated Drug-Drug Interactions of Flumatinib as Both a Victim and a Perpetrator. [PDF]

Drug Des Devel Ther
Alifu M, Chu X, Zhu X, Mak WY, Zheng A, Pan C, He Q, Zhu X, Kuai Z, Xiang X.   +9 more
europepmc   +1 more source

Exploring the roles of cytochrome P450 enzymes and their inhibitors in cancers and non-neoplastic human diseases. [PDF]

Arch Pharm Res
Lee H, Kwon YJ, Chun YJ.
europepmc   +1 more source

CYP2C8-Mediated Drug-Drug Interactions and the Factors Influencing the Interaction Magnitude. [PDF]

Drug Des Devel Ther
Zhu LL, Yu LY, Wang YH, Zhou Q.
europepmc   +1 more source

Comprehensive In Vitro Metabolic Characterization of Eudesmin in Human and Mouse Hepatocytes. [PDF]

Pharmaceutics
Lee MS, Kim JH, Song IS, Cho YY, Lee JY, Lee HS.   +5 more
europepmc   +1 more source

New Mechanistic Evidence for Perfluorodecanoic Acid (PFDA) Teratogenicity via CYP26A1-Mediated Retinoic Acid Metabolism and Signaling. [PDF]

Chem Res Toxicol
Hvizdak M, Kandel SE, Lampe JN.
europepmc   +1 more source