Results 101 to 110 of about 10,726 (197)
CYP2C8-Mediated Drug–Drug Interactions and the Factors Influencing the Interaction Magnitude
Drug Design, Development and TherapyLing-Ling Zhu,1,* Ling-Yan Yu,2,* Yan-Hong Wang,2 Quan Zhou2 1VIP Care and Geriatric Ward, Division of Nursing, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of ...
Zhu LL, Yu LY, Wang YH, Zhou Q
doaj
, 2019 Problema: La respuesta terapéutica antimalárica depende de múltiples determinantes asociados con el plasmodio (especie, mutaciones, cantidad, etc.) y al hospedero (nutrición, genes, metabolismo, etc.), pero los últimos son poco conocidos.
Carmona Fonseca, Jaime +2 more
core
Polymorphisms of CYP2C8 Alter First-Electron Transfer Kinetics and Increase Catalytic Uncoupling
, 2019 Cytochrome P450 2C8 (CYP2C8) epoxygenase is responsible for the metabolism of over 60 clinically relevant drugs, notably the anticancer drug Taxol (paclitaxel, PAC).
Daryl D. Meling +4 more
core +1 more source
Influence ofCYP2C8*13andCYP2C8*14Alleles on AmiodaroneN‐Deethylation [PDF]
Basic & Clinical Pharmacology & Toxicology, 2011 Nobumitsu, Hanioka +3 more
openaire +2 more sources
Clinical studies on pharmacokinetic drug-drug interactions caused by clopidogrel : Focus on CYP2C8-mediated drug metabolism [PDF]
, 2019 Clopidogrel, an adenosine diphosphate receptor subtype P2Y12 antagonist, attenuates platelet activation via its active cis-thiol metabolite formed in two steps predominantly by cytochrome P450 (CYP) 2C19 and CYP3A4.
Itkonen, Matti
core
CYP2C8 genotype significantly alters imatinib metabolism in chronic myeloid leukaemia patients
, 2017 Objective: The aims of this study were to determine the effects of the CYP2C8*3 and *4 polymorphisms on imatinib metabolism and plasma imatinib concentrations in chronic myeloid leukaemia (CML) patients.
Somogyi, A. +6 more
core +1 more source