Impact of CYP2C9, CYP2C19 and ABCB1 genetic polymorphisms on antiepileptic drug safety and efficacy
A review of literature data is presented on polymorphic variants of genes responsible for antiepileptic drugs (AEDs) pharmacokinetics: highly polymorphic cytochrome P450 isoenzyme genes CYP2C9 and CYP2C19 as well as the gene ABCB1 encoding transporter ...
N. A. Galankin +4 more
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The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen [PDF]
Elizabeth Sconce +9 more
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GENETIC POLYMORPHISM OF CYTOCHROMES P450 2C9 AND 2C19 IN SLOVENIAN POPULATION
Background. Cytochrome P450 2C9 (CYP2C9) and 2C19 (CYP2C19) participate in metabolism of many clinically important drugs. Genetic polymorphisms of the CYP2C9 and CYP2C19 genes are described which may affect drug treatment.
Darja Herman +2 more
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In pediatric patients, age has more impact on dosing of vitamin K antagonists than VKORC1 or CYP2C9 genotypes [PDF]
Ulrike Nowak‐Göttl +6 more
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Warfarin and celecoxib interaction in the setting of cytochrome P450 (CYP2C9) polymorphism with bleeding complication [PDF]
Harshveer Malhi +3 more
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Effect of iguratimod on diclofenac metabolism by CYP2C9 in rats and human recombinant CYP2C9 yeast cells [PDF]
Muhammad Usman +7 more
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CYP2C9 polymorphisms in epilepsy: influence on phenytoin treatment
Carlos Eduardo Silvado,1 Vera Cristina Terra,1 Carlos Alexandre Twardowschy2 1Comprehensive Epilepsy Program, Hospital de Clinicas, Federal University of Parana (UFPR), Curitiba, Brazil; 2Department of Neurology, Catholic University of Parana (PUCPR ...
Silvado CE, Terra VC, Twardowschy CA
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