Results 1 to 10 of about 2,707,171 (199)
Altered DNA methylation of CYP2E1 gene in schizophrenia patients with tardive dyskinesia [PDF]
BMC Medical Genomics, 2022 Background About 20–30% of patients with schizophrenia develop tardive dyskinesia (TD). Oxidative stress is one potential causes of TD. CYP2E1 is considered as an oxidative stress-related gene, however, no study has been reported on the DNA methylation ...
Ping Zhang +9 more
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Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis [PDF]
Journal of Oral Biology and Craniofacial Research, 2012 : Background: Oral carcinogenesis is a complex process affected by genetic as well as environmental factors. CYP2E1 gene is involved in metabolism of number of compounds and carcinogens. Its normal functioning is required for homeostasis of free radical.
Rahul Pandey +6 more
doaj +5 more sources
HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells. [PDF]
PLoS ONE, 2014 CYP2E1, one of the cytochrome P450 mixed-function oxidases located predominantly in liver, plays a key role in metabolism of xenobiotics including ethanol and procarcinogens. Recently, down-expression of CYP2E1 was found in hepatocellular carcinoma (HCC)
Hongming Liu +6 more
doaj +2 more sources
The Correlation of Cyp2e1 Genetic Polymorphism on Alcohol Drinking Habits in Papuan Ethnicity [PDF]
Mutiara Medika, 2021 Alcohol abuse is associated with genetic factors and is influenced by certain races and ethnicities. CYP2E1, which works on the endoplasmic reticulum, produces an enzyme that plays a significant role in alcohol metabolism.
Mardhatillah Marsa +3 more
doaj +4 more sources
No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population
Journal of the Formosan Medical Association, 2018 Cytochrome P450 2E1 (CYP2E1) gene is one of the candidate genes for alcohol dependence (AD). Four single nucleotide polymorphisms (SNPs) of CYP2E1 gene (CYP2E1*1D, *5B, *6 and *1B) have been associated with AD previously in other ethnic populations.
Cho-Yin Huang +4 more
doaj +2 more sources
Integrated evaluation of environmental monitoring, rheumatoid arthritis biomarkers, and genetic variants in textile dyeing workers [PDF]
Journal of the Egyptian Public Health AssociationBackground Workers in the textile dyeing industry are occupationally exposed to high concentrations of particulates and volatile organic compounds (VOCs). This work aimed to study the environment-gene interaction as a risk factor for rheumatoid arthritis
Amal Saad-Hussein +7 more
doaj +2 more sources
Saudi Pharmaceutical Journal, 2021 Objectives Cytochrome P450 2E1 (CYP2E1) is one of the major enzymes involved in the metabolism and detoxification of various drugs and xenobiotics. Polymorphisms in the CYP2E1 gene exhibit high inter-individual variations associated with alterations in ...
Lenah S. Binmahfouz, Amina M. Bagher
doaj +1 more source
Tropical Animal Science Journal, 2021 The aim of this study was to conduct the genotyping of the single nucleotide polymorphism (SNP) in g.50657948 T>G of the CYP2E1 gene and its relation to the carcass and meat quality. A total of 200 Indonesian lambs consisted of 20 Javanese fat-tail sheep
R. S. Harahap, R. R. Noor, A. Gunawan
doaj +1 more source
Genetic polymorphisms in CYP2E1: association with schizophrenia susceptibility and risperidone response in the Chinese Han population. [PDF]
PLoS ONE, 2012 CYP2E1 is a member of the cytochrome P450 superfamily, which is involved in the metabolism and activation of both endobiotics and xenobiotics. The genetic polymorphisms of CYP2E1 gene (Chromosome 10q26.3, Accession Number NC_000010.10) are reported to be
Ran Huo +12 more
doaj +1 more source
BMC Research Notes, 2021 Objective The risk of contracting tuberculosis (TB) and the efficacy of TB therapy are affected by several factors, including genetic variation among populations.
Melisa Intan Barliana +10 more
doaj +1 more source