Results 11 to 20 of about 2,707,171 (199)
Zaporožskij Medicinskij Žurnal, 2014 Aim. The effectiveness of treatment of chronic hepatitis C (CHC) depends on the genetic characteristics of the patients. The aim was to analyze the association of CYP2E1*6 polymorphism with the risk of development and severity of CHC.
V. V. Godovan, K. V. Ostapchuk
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The Functional Identification of the CYP2E1 Gene in the Kidney of Lepus yarkandensis. [PDF]
Int J Mol SciThis study aims to identify the function of the cytochrome P450 2E1 (CYP2E1) gene in the kidneys of Lepus yarkandensis. CYP2E1 is a significant metabolic enzyme involved in the metabolism of various endogenous and exogenous compounds and is associated with the occurrence and progression of multiple diseases. Given L.
Shao D +5 more
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Horticultural Plant Journal, 2015 Cytochrome P450 CYP2E1 is mainly present in hepatocytes in the livers of mammals, where it plays an important role in the metabolism of xenobiotic organic substances.
Wang Man +5 more
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Brazilian Journal of Infectious Diseases, 2019 Setting: Treatment of tuberculosis (TB) can result in Drug-Induced Liver Injury (DILI) since hepatotoxic metabolites are formed during the biotransformation of isoniazid (INH).DILI can be related to the genetic profile of the patient.
Eliana Abreu Santos +7 more
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Polymorphisms in the CYP2E1 and GSTM1 Genes as Possible Protection Factors for Leprosy Patients
PLoS ONE, 2012 The CYP2E1 and GSTM1 genes encode metabolic enzymes that have key functions in drug modification and elimination.We investigated the possible effects of CYP2E1 and GSTM1 polymorphisms in 71 leprosy patients and in 110 individuals from the general population. The GSTM1*0 null allele and INDEL CYP2E1*1D mutant genotypes were analyzed by conventional PCR,
Pablo Pinto +6 more
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Genetics and Molecular Biology, 2011 The CYP2E1 protein belongs to the P450 enzymes family and plays an important role in the metabolism of small molecular and organic pollutants. In this study we generated CYP2E1 transgenic plants of Petunia using Agrobacterium rhizogenes K599.
Daoxiang Zhang +3 more
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Effect of SNPs in the Promoter Region on the Expression of Cytochrome P450 2E1 (CYP2E1) in Pig Liver
AnimalsBoar taint, an unfavorable odor in the meat of intact male pigs, is caused primarily by the accumulation of two compounds: androstenone and skatole. This multifactorial trait is regulated by numerous dietary, management and genetic factors.
Holly Archer +5 more
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Effect of grapefruit juice on CYP2E1 gene expression in obese and control rats
مجله دانشگاه علوم پزشکی بیرجند, 2021 Background and Aims: The CYP2E1 gene encodes cytochrome P450 enzymes that play an essential role in liver fat metabolism. Additionally, grapefruit reduces plasma lipids in the body.
Parisa Vahid, Noosha Zia-Jahromi
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Next-Generation Sequencing and Bioinformatics-Based Protocol for the Full-Length CYP2E1 Gene Polymorphism Analysis. [PDF]
Pharmgenomics Pers Med, 2022 INTRODUCTION: Pharmacogenetics studies provide clinically relevant information on the identified associations between genetic variants and individual variability in drug response, which, in turn, offers great promise for guiding personalized drug therapy
Igumnova V +4 more
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Study of cyp2E1 gene RsaI/PstI polymorphisms in patients with gastric cancer in north of Iran
Research in Molecular Medicine, 2016 Background: North of Iran is amongst high incidence rate areas of gastric carcinoma where environmental carcinogenic compounds especially agricultural pesticides are massively used.
Samaneh Kamalipour +3 more
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