Results 21 to 30 of about 25,509 (198)
The inhibition curves of VDL on five CYP450 isoforms ( ± s, n = 6).
, 2023 The inhibition curves of VDL on five CYP450 isoforms ( ± s, n = 6).
Yiran Jin (15864387) +5 more
core +1 more source
Journal of Arthropod-Borne Diseases, 2021 Background: Cytochrome P450-dependent monooxygenases are a very important metabolic system involve in insecticide resistance. This study was conducted to find the association between the expression level of cytochrome P450 (CYP450) and permethrin ...
Azimeh Ghaderi +2 more
doaj +1 more source
Angewandte Chemie, EarlyView.A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang +15 more
wiley +2 more sources
Stereoselective metabolism of verapamil and four other chiral drugs by cDNA expressed CYP450's.
, 2003 Stereoselective metabolism of verapamil and four other chiral drugs by cDNA expressed CYP450 ...
Lixin. Shen (8000276)
core +4 more sources
HCIP: An Online database for prediction CYP450 Enzyme Inhibition potential of bioactive compounds [PDF]
, 2021 Background: Concomitant administration of herbal medicine and conventional may lead to severe metabolism-oriented herb-drug interactions. However, detecting herb-drug interaction is expensive and higher time-consuming.
Dhanasekaran, Dhivya +13 more
core +1 more source
Regulation of Porcine Hepatic Cytochrome P450 — Implication for Boar Taint
Computational and Structural Biotechnology Journal, 2014 Cytochrome P450 (CYP450) is the major family of enzymes involved in the metabolism of several xenobiotic and endogenous compounds. Among substrates for CYP450 is the tryptophan metabolite skatole (3-methylindole), one of the major contributors to the off-
Martin Krøyer Rasmussen +1 more
doaj +1 more source
Toxics, 2022 The cytochromes P450 (CYP450) represent a major enzyme family operating mostly in the first step of xenobiotic detoxification in aquatic organisms. The ability to measure these CYP450 enzymes’ activities provides a crucial tool to understand organisms ...
Elodie Melo de Almeida +3 more
doaj +1 more source
, 2016 The heme is shown is each model as a space-filling projection. The J and J’ helices in rabbit CYP450 2C5, which are absent in S. mansoni CYP450, are highlighted in yellow.
Ethan M. S. Fisher (841520) +6 more
core +1 more source
, 2019 Western blotting analysis of CYP450 2B. Data were obtained as media ± standard deviation and graphically represented as fold change vs. N. Significant of difference between groups is shown: ***p.001 vs. N; ##p.01 vs. D.
Vincenzo Migliaccio (6635675) +4 more
core +1 more source
Chemical structures of CYP450 inhibitors used in this study.
, 2016 Chemical structures of CYP450 inhibitors used in this study.
Ethan M. S. Fisher (841520) +6 more
core +1 more source