Results 51 to 60 of about 4,157 (190)
BMC Cardiovascular Disorders, 2018 Background The anticoagulation of atrial fibrillation catheter ablation during the perioperative stage does matter and should be treated with discretion. We aimed to assess impact of three important genes participating in vitamin K cycle (i.e.
Jiao Li +5 more
doaj +1 more source
Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? [PDF]
, 2018 Obesity is one of the major epidemics of this millennium, and its incidence is growing worldwide. Following the epidemics of obesity, nonalcoholic fatty liver disease (NAFLD) has become a disease of increasing prevalence and a leading cause of morbidity ...
El Hadi, Hamza +2 more
core +2 more sources
Interethnic variability of CYP4F2 (V433M) in admixed population of Roma and Hungarians [PDF]
Environmental Toxicology and Pharmacology, 2015 Pharmacogenetic based dosing recommendations are provided in FDA-approved warfarin label for Caucasians. Evidence of notable difference in dosing algorithms of under-represented populations forced us to explore the genetic variability of CYP4F2 gene in Roma and Hungarian populations.484 Roma, 493 Hungarian untreated subjects were genotyped for the ...
Csilla, Sipeky +10 more
openaire +2 more sources
Medicine, 2023 Acute ischemic stroke is a major cause of morbidity and mortality worldwide, and genetic factors play a role in the risk of stroke. Single nucleotide polymorphisms (SNPs) in the VKORC1, CYP4F2, and GGCX genes have been linked to clinical outcomes, such as bleeding and cardiovascular diseases.
Iluţ, Silvina +11 more
openaire +2 more sources
Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation [PDF]
, 2019 Adipocytes are the most important cell type in adipose tissue playing key roles in immunometabolism. We previously reported that nine members of the Toll-like receptor (TLR) family are expressed in an originally established porcine intramuscular pre ...
Albarracín, Leonardo Miguel +13 more
core +1 more source
Genetic polymorphisms of VKORC1, CYP2C9, CYP4F2 in Bai-, Zang-Chinese [PDF]
Heart, 2011 This study aims to detect the popular polymorphisms in VKORC1, CYP2C9 and CYP4F2 in Bai-, Zang-Chinese, to start the exploration of better use of warfarin in Chinese minorities. Methods 370 healthy, unrelated individuals were enrolled, including 131 Han-Chinese, 132 Bai-Chinese?
openaire +1 more source
Increased α‐tocopherol metabolism in horses with equine neuroaxonal dystrophy
Journal of Veterinary Internal Medicine, 2021 Background Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder associated with a vitamin E deficiency within the first year of life.
Erin N. Hales +21 more
doaj +1 more source
SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping [PDF]
, 2010 Background PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction enzyme sites is challenging and cumbersome.
Hsueh-Wei Chang +3 more
core +2 more sources
Pharmacogenetics of warfarin: A literature review [PDF]
КардиоСоматикаWarfarin is an oral indirect anticoagulant that is widely used for the prevention of thromboembolic events. Pharmacogenetic testing is the most promising approach to personalizing warfarin treatment. In this review, we aimed to summarize how the patients’
Nadezhda V. Izmozherova +4 more
doaj +1 more source
MIRNA-DISTILLER: A Stand-Alone Application to Compile microRNA Data from Databases [PDF]
, 2011 MicroRNAs (miRNA) are small non-coding RNA molecules of ~22 nucleotides which regulate large numbers of genes by binding to seed sequences at the 3’-UTR of target gene transcripts.
Jessica K. Rieger +2 more
core +1 more source