Results 51 to 60 of about 10,826 (180)
Interactions of the Gasotransmitters Contribute to Microvascular Tone (Dys)regulation in the Preterm Neonate [PDF]
, 2015 Background & Aims Hydrogen sulphide (H2S), nitric oxide (NO), and carbon monoxide (CO) are involved in transitional microvascular tone dysregulation in the preterm infant; however there is conflicting evidence on the interaction of these ...
Chwatko, Grażyna +6 more
core +13 more sources
Contribution of hydrogen sulfide to the control of coronary blood flow [PDF]
, 2014 This study examined the mechanisms by which H2S modulates coronary microvascular resistance and myocardial perfusion at rest and in response to cardiac ischemia. Experiments were conducted in isolated coronary arteries and in open-chest anesthetized dogs.
Berwick, Zachary C. +5 more
core +1 more source
, 2009 The endothelium controls vascular tone not only by releasing NO and prostacyclin, but also by other pathways causing hyperpolarization of the underlying smooth muscle cells.
Félétou, M, VanHoutte, PM
core +1 more source
mBio, 2019 The reverse transsulfuration pathway is the major route for the metabolism of sulfur-containing amino acids. The role of this metabolic pathway in macrophage response and function is unknown. We show that the enzyme cystathionine γ-lyase (CTH) is induced
Alain P. Gobert +15 more
doaj +1 more source
Human Cystathionine γ-Lyase Is Inhibited by s-Nitrosation: A New Crosstalk Mechanism between NO and H2S. [PDF]
Antioxidants (Basel), 2021 The ‘gasotransmitters’ hydrogen sulfide (H2S), nitric oxide (NO), and carbon monoxide (CO) act as second messengers in human physiology, mediating signal transduction via interaction with or chemical modification of protein targets, thereby regulating ...
Fernandes DGF +7 more
europepmc +2 more sources
N-acetylcysteine serves as substrate of 3-mercaptopyruvate sulfurtransferase and stimulates sulfide metabolism in colon cancer cells [PDF]
, 2019 Hydrogen sulfide (H2S) is an endogenously produced signaling molecule. The enzymes 3-mercaptopyruvate sulfurtransferase (MST), partly localized in mitochondria, and the inner mitochondrial membrane-associated sulfide:quinone oxidoreductase (SQR), besides
Forte, Elena +8 more
core +2 more sources
Scientific Reports, 2021 Triple-negative breast cancer (TNBC) is a high-risk subtype of breast cancer with high capacity for metastasis and lacking of therapeutic targets.
semanticscholar +1 more source
Evidence of endogenously produced hydrogen sulfide (H2S) and persulfidation in male reproduction
Scientific Reports, 2022 Persulfidation contributes to a group of redox post-translational modifications (PTMs), which arise exclusively on the sulfhydryl group of cysteine as a result of hydrogen sulfide (H2S) action.
Hedvika Řimnáčová +11 more
doaj +1 more source
Redox Biology, 2021 During pregnancy, estrogen (E2) stimulates uterine artery blood flow (UBF) by enhancing nitric oxide (NO)-dependent vasodilation. Cystathionine γ-lyase (CSE) promotes vascular NO signaling by producing hydrogen sulfide (H2S) and by maintaining the ratio ...
Rachael Bok +10 more
doaj +1 more source
A cardioprotective insight of the cystathionine γ-lyase/hydrogen sulfide pathway
International Journal of Cardiology: Heart & Vasculature, 2015 Traditionally, hydrogen sulfide (H2S) was simply considered as a toxic and foul smelling gas, but recently H2S been brought into the spot light of cardiovascular research and development.
Steve Huang, Hua Li, Junbo Ge
doaj +1 more source