Results 51 to 60 of about 12,014 (181)

Contribution of hydrogen sulfide to the control of coronary blood flow [PDF]

open access: yes, 2014
This study examined the mechanisms by which H2S modulates coronary microvascular resistance and myocardial perfusion at rest and in response to cardiac ischemia. Experiments were conducted in isolated coronary arteries and in open-chest anesthetized dogs.
Berwick, Zachary C.   +5 more
core   +1 more source

N-acetylcysteine serves as substrate of 3-mercaptopyruvate sulfurtransferase and stimulates sulfide metabolism in colon cancer cells [PDF]

open access: yes, 2019
Hydrogen sulfide (H2S) is an endogenously produced signaling molecule. The enzymes 3-mercaptopyruvate sulfurtransferase (MST), partly localized in mitochondria, and the inner mitochondrial membrane-associated sulfide:quinone oxidoreductase (SQR), besides
Forte, Elena   +8 more
core   +2 more sources

Hydrogen Sulfide Mitigates Myocardial Infarction via Promotion of Mitochondrial Biogenesis-Dependent M2 Polarization of Macrophages. [PDF]

open access: yes, 2016
Published onlineJOURNAL ARTICLEAIMS: Macrophages are of key importance for tissue repair after myocardial infarction (MI). Hydrogen sulfide (H2S) has been shown to exert cardioprotective effects in MI.
Miao, L   +7 more
core   +1 more source

Biomineralized CdS quantum dot nanocrystals: optimizing synthesis conditions and improving functional properties by surface modification [PDF]

open access: yes, 2016
An engineered strain of Stenotrophomonas maltophilia (SMCD1) is capable of the direct extracellular biomineralization of CdS quantum dot nanocrystals from buffered aqueous solution of cadmium acetate and l-cysteine without the addition of a chemically ...
Berger, Bryan W.   +4 more
core   +3 more sources

Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway

open access: yesmBio, 2019
The reverse transsulfuration pathway is the major route for the metabolism of sulfur-containing amino acids. The role of this metabolic pathway in macrophage response and function is unknown. We show that the enzyme cystathionine γ-lyase (CTH) is induced
Alain P. Gobert   +15 more
doaj   +1 more source

Cystathionine γ-lyase promotes estrogen-stimulated uterine artery blood flow via glutathione homeostasis

open access: yesRedox Biology, 2021
During pregnancy, estrogen (E2) stimulates uterine artery blood flow (UBF) by enhancing nitric oxide (NO)-dependent vasodilation. Cystathionine γ-lyase (CSE) promotes vascular NO signaling by producing hydrogen sulfide (H2S) and by maintaining the ratio ...
Rachael Bok   +10 more
doaj   +1 more source

A novel cystathionine γ-lyase inhibitor, I194496, inhibits the growth and metastasis of human TNBC via downregulating multiple signaling pathways

open access: yesScientific Reports, 2021
Triple-negative breast cancer (TNBC) is a high-risk subtype of breast cancer with high capacity for metastasis and lacking of therapeutic targets.

semanticscholar   +1 more source

Evidence of endogenously produced hydrogen sulfide (H2S) and persulfidation in male reproduction

open access: yesScientific Reports, 2022
Persulfidation contributes to a group of redox post-translational modifications (PTMs), which arise exclusively on the sulfhydryl group of cysteine as a result of hydrogen sulfide (H2S) action.
Hedvika Řimnáčová   +11 more
doaj   +1 more source

A cardioprotective insight of the cystathionine γ-lyase/hydrogen sulfide pathway

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2015
Traditionally, hydrogen sulfide (H2S) was simply considered as a toxic and foul smelling gas, but recently H2S been brought into the spot light of cardiovascular research and development.
Steve Huang, Hua Li, Junbo Ge
doaj   +1 more source

The therapeutic potential for targeting CSE/H2S signaling in macrophages against Escherichia coli infection

open access: yesVeterinary Research, 2023
Macrophages play a pivotal role in the inflammatory response to the zoonotic pathogen E. coli, responsible for causing enteric infections. While considerable research has been conducted to comprehend the pathogenesis of this disease, scant attention ...
Shaodong Fu   +4 more
doaj   +1 more source

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