Results 21 to 30 of about 1,391 (117)

1,25‐dihydroxyvitamin D 3 influences cellular homocysteine levels in murine preosteoblastic MC3T3‐E1 cells by direct regulation of cystathionine β‐synthase [PDF]

, 2011
High homocysteine (HCY) levels are a risk factor for osteoporotic fracture. Furthermore, bone quality and strength are compromised by elevated HCY owing to its negative impact on collagen maturation.
Boonen, Bouillon, Bouillon, Chiku, Daci, Eberhardt, Finkelstein, Garcion, Ge, Heaney, Herrmann, Hofbauer, Kang, Kim, Koh, Kolhouse, Kriebitzsch, Levasseur, Lips, Liu, Lubec, McLean, Meyer, Mosharov, Prudova, Raposo, Robert, Rodan, Rosen, Saito, Saposnik, Schuster, Selhub, Singh, Stipanuk, Taoka, van Guldener, van Meurs, Verlinden, Vitvitsky, Wang   +40 more
core   +3 more sources

Propargylglycine inhibits hypotaurine/taurine synthesis and elevates cystathionine and homocysteine concentrations in primary mouse hepatocytes [PDF]

, 2015
Our investigation showed that hepatocytes isolated from cysteine dioxygenase knockout mice (Cdo1(−/−)) had lower levels of hypotaurine and taurine than Cdo1(+/+) hepatocytes. Interestingly, hypotaurine accumulates in cultured wild-type hepatocytes.
Halina Jurkowska, Heather B. Roman, Lawrence L. Hirschberger, Martha H. Stipanuk   +3 more
core   +1 more source

H2S biosynthesis and catabolism: new insights from molecular studies [PDF]

, 2017
Hydrogen sulfide (H2S) has profound biological effects within living organisms and is now increasingly being considered alongside other gaseous signalling molecules, such as nitric oxide (NO) and carbon monoxide (CO).
A Asimakopoulou, A Badiei, A Badiei, A Calderwood, A Jamroz-Wiśniewska, A Kalani, A Madurga, A Papapetropoulos, A Sun, AA Untereiner, AD Ang, AF Kamath, AF Perna, AF Perna, AK Mustafa, AL King, B Calenic, B Fox, B Gemici, B Gemici, B Geng, B Geng, B Qabazard, B Qabazard, B Szczesny, BD Paul, BJ Henriques, C Coletta, C Hine, C Hine, C Konrad, C Köhn, C Maestro de las Casas, C Steegborn, C Szabo, C Yang, CW Huang, D Liang, D Liao, DA Wing, DC Croteau-Chonka, DI Zafeiriou, DL Miller, DW Porter, DW Porter, E Albertini, E Grambow, E Lagoutte, EG Lynn, EG Mueller, EG Shesely, EM Bos, F Talaei, FL Zhao, G Chwatko, G Szabo, G Tang, G Tang, G Wang, G Yang, G Yang, G Yang, G Yang, G Yang, G Yang, G Yang, G Yang, G Yang, G Zagli, G Zhang, GA Benavides, GD Yang, GK Kolluru, GV Velmurugan, H Duplain, H Jang, H Jurkowska, H Kabil, H Li, H Shi, H Zhang, HB Roman, HG Lee, HL Jiang, HS Jin, I Baiges, I Billaut-Laden, I Hirata, I Ishii, I Meo Di, I Ueki, J Cai, J Candela, J Ereño-Orbea, J Hamelet, J Hamelet, J Wang, J Wang, JB Vicente, JD Finkelstein, JG Vande Weghe, JJ Li, JL Meng, JL Wallace, JN Mayo, JT Brosnan, JW Calvert, JW Elrod, JW Horsman, K Eto, K Kondo, K Modis, K Módis, K Módis, K Ono, K Robert, K Wang, K Wilson, K Yao, KL Flannigan, KM Syhr, KN Maclean, KR Olson, KR Olson, L Chang, L Chen, L Gambari, L Li, L Li, L Li, L Li, L Miao, L Miao, L Wang, L Wang, L Xei, LA Harker, LL Pan, M Ackermann, M Goubern, M Liang, M Libiad, M Meier, M Nuño-Ayala, M Okomoto, M Pimentel, M Watanabe, M Whiteman, M Whiteman, M Whiteman, M Whiteman, M Whiteman, M Yang, MA Guzman, MD Fonseca, MH Stipanuk, MH Stipanuk, MK Thorson, MK Thorson, MM Cortese-Krott, MM Cortese-Krott, MP Gallegos-Arreola, MR Filipovic, MR Filipovic, MR Jackson, MW Budde, MY Ali, MY Tsai, N Endo, N Nagahara, N Nagahara, N Shibuya, N Weiss, O Kabil, O Kabil, O Kabil, O Kabil, O Zayachkivska, P Manna, P Nicholls, Peter Rose, Philip K. Moore, PK Yadav, PM Mrozikiewicz, PM Snijder, PS Ganapathy, Q Hu, QH Meng, R Baskar, R Ding, R Greiner, R Kodela, R Picton, R Tocmo, R Tocmo, R Wang, R Yang, RC Zanardo, RH Abeles, RN Carter, RS Beard, S Banu, S Bhattacharyya, S Dayal, S Dayal, S Gupta, S Huang, S Jain, S Jin, S Kundu, S Mani, S Pushpakumar, S Ramasamy, S Saha, S Sen, S Shastry, S Shi, S Xu, SH Cheung, SK Jain, SR Lentz, SY Wu, T Ida, T Itou, T Ivanciuc, T Krejcova, T Takahashi, TJ Lechuga, TM Hildbrant, TT Pan, TW Miller, U Sen, U Sen, U Sen, V Tiranti, V Vitvisky, VE Laubach, W Liu, W Qiao, W Wang, W Washtien, W Zhao, W Zhu, WA Pryor, WJ Cai, X Li, X Shen, X Shen, XH Wang, XQ Tang, XQ Tang, Y Gao, Y Hagiya, Y Hu, Y Kimura, Y Kumai, Y Li, Y Liu, Y Pei, Y Shen, Y Wei, Y Xu, Y Zhou, Yi Zhun Zhu, YJ Peng, Z Guo, Z Jiang, Z Pan, Z Wang, Z Zhang, ZL Clarke, ZZ Xie, ZZ Zhao   +272 more
core   +2 more sources

Effect of S-Allyl -L-Cysteine on MCF-7 cell Line 3-mercaptopyruvate sulfurtransferase/sulfane sulfur system, viability and apoptosis [PDF]

, 2020
The S-Allyl-L-cysteine (SAC) component of aged garlic extract (AGE) is proven to have anticancer, antihepatotoxic, neuroprotective and neurotrophic properties.
Bentke, Anna, Bronowicka-Adamska, Patrycja, Lasota, Małgorzata, Wróbel, Maria   +3 more
core   +1 more source

Hydrogen sulfide and inflammatory joint diseases [PDF]

, 2017
[Abstract] Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are widespread rheumatic diseases characterized by persistent inflammation and joint destruction. Hydrogen sulfide (H2S) is an endogenous gas with important physiologic functions in
Blanco García, Francisco J, Burguera, Elena F., Meijide-Faílde, Rosa   +2 more
core   +2 more sources

Znaczenie polimorfizmów rs1021737 i rs482843 gamma-liazy cystationinowej w etiologii stanu przedrzucawkowego w populacji kaukaskiej [PDF]

, 1970
Introduction: Recently, an increasing number of reports indicate the participation of genetic factors in the pathogenesis of preeclampsia (PE). The genes involved in the synthesis of nitric oxide that participates in the vasolidation, may play an ...
Bartkowiak-Wieczorek, Joanna, Bogacz, Anna, Czerny, Bogusław, Drews, Krzysztof, Grześkowiak, Edmund, Mrozikiewicz, Przemysław M., Omielańczyk, Magdalena, Seremak-Mrozikiewicz, Agnieszka, Wolski, Hubert   +8 more
core   +2 more sources

The effects of graded levels of calorie restriction : XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome [PDF]

, 2017
We would like to acknowledge the BSU staff for their invaluable help with caring for the animals.Peer reviewedPublisher ...
Chen, Luonan, Derous, Davina, Douglas, Alex, Green, Cara L, Han, Jing-Dong J, Lusseau, David, Mitchell, Sharon E, Promislow, Daniel E L, Speakman, John R, Wang, Lu, Wang, Yingchun   +10 more
core   +1 more source

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs. [PDF]

, 2023
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous regulator of a broad range of physiological functions. H2S belongs to the class of molecules known as gasotransmitters, which typically include nitric oxide (NO) and carbon ...
Cirino G, Papapetropoulos A, Szabo C
core   +1 more source

Inhibition of Prostaglandin Reductase 2, a Putative Oncogene Overexpressed in Human Pancreatic Adenocarcinoma, Induces Oxidative Stress-Mediated Cell Death Involving xCT and CTH Gene Expressions through 15-Keto-PGE2.

PLoS ONE, 2016
Prostaglandin reductase 2 (PTGR2) is the enzyme that catalyzes 15-keto-PGE2, an endogenous PPARγ ligand, into 13,14-dihydro-15-keto-PGE2. Previously, we have reported a novel oncogenic role of PTGR2 in gastric cancer, where PTGR2 was discovered to ...
Emily Yun-Chia Chang, Yi-Cheng Chang, Chia-Tung Shun, Yu-Wen Tien, Shu-Huei Tsai, Siow-Wey Hee, Ing-Jung Chen, Lee-Ming Chuang   +7 more
doaj   +1 more source

Hydrogen sulfide generation from l-cysteine in the human glioblastoma-astrocytoma U-87 MG and neuroblastoma SHSY5Y cell lines [PDF]

, 2017
Hydrogen sulfide (H2S) is endogenously synthesized from l-cysteine in reactions catalyzed by cystathionine beta-synthase (CBS, EC 4.2.1.22) and gamma-cystathionase (CSE, EC 4.4.1.1).
Bentke, Anna, Bronowicka-Adamska, Patrycja, Wróbel, Maria   +2 more
core   +1 more source