Results 51 to 60 of about 41,311 (257)
Annals of Neurology, EarlyView.Objective Plasma biomarkers of Alzheimer's disease (AD) pathology are frequently tested in specialized research settings, which limits the generalizability of findings. Using electronic health records and banked plasma, we evaluated plasma biomarkers—phosphorylated tau 217 (p‐tau217), β‐amyloid 1–42/1–40 (Aβ42/Aβ40) and p‐tau217/Aβ42—in a real‐world ...
Katheryn A.Q. Cousins +12 more
wiley +1 more source
Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?
Arthritis &Rheumatology, EarlyView.Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin +11 more
wiley +1 more source
Glomerular and Tubular Functions in Children and Adults with Transfusion-Dependent Thalassemia
Turkish Journal of Hematology, 2018 This study aimed at assessing renal functions in patients with transfusion-dependent thalassemia (TDT). Fifty patients and 30 controls were enrolled in this prospective study. Serum levels of electrolytes and albumin were measured by a spectrophotometer.
Agageldi Annayev +5 more
doaj +1 more source
GFR Estimation After Cystatin C Reference Material Change
Kidney International Reports, 2021 Introduction: Glomerular filtration rate (GFR) is routinely estimated with cystatin C. In June 2010, the International Federation of Clinical Chemistry (IFCC) released a certified cystatin C reference material (ERM-DA471/IFCC), and new cystatin C ...
Stefanie W. Benoit +7 more
doaj +1 more source
Dyslipidemia and serum cystatin C levels as biomarker of diabetic nephropathy in patients with type 2 diabetes mellitus [PDF]
, 2023 Tadesse Asmamaw Dejenie +17 more
openalex +1 more source
Cystatin and glomerular filtration rate equations in old renal transplant donors
The Egyptian Journal of Internal Medicine, 2019 Introduction Early detection of renal dysfunction in live kidney donors is important and needs easy reliable tools. The aim of the study is to evaluate the cystatin level and cystatin-based equation in assessment of renal function in old healthy kidney ...
Ahmed Y Ali, Sahier O Elkhashab
doaj +1 more source
Cystatin C in Alzheimer's disease [PDF]
Frontiers in Molecular Neuroscience, 2012 Changes in expression and secretion levels of cystatin C (CysC) in the brain in various neurological disorders and in animal models of neurodegeneration underscore a role for CysC in these conditions. A polymorphism in the CysC gene (CST3) is linked to increased risk for Alzheimer's disease (AD).
Kaur, Gurjinder, Levy, Efrat
openaire +3 more sources
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo +10 more
wiley +1 more source
The Carboxypeptidase Activity of Cathepsin X is Not Controlled by Endogenous Inhibitors
Acta Chimica Slovenica, 2019 Cysteine cathepsins are peptidases with housekeeping functions that play different specific roles in different tissues. Endogenous peptidase inhibitors, such as cystatins and thyropins are the ultimate way of controlling their activity.
Urša Pečar Fonović +4 more
doaj +1 more source
Association Cystatin C and Risk of Stroke in Elderly Patients With Obstructive Sleep Apnea: A Prospective Cohort Study [PDF]
, 2021 Xiaofeng Su +12 more
openalex +1 more source