Results 191 to 200 of about 3,506 (234)
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Biochemical Society Symposia, 2003
Chicken egg white cystatin was first described in the late 1960s. Since then, our knowledge about a superfamily of similar proteins present in mammals, birds, fish, insects, plants and some protozoa has expanded, and their properties as potent peptidase inhibitors have been firmly established.
Magnus, Abrahamson +2 more
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Chicken egg white cystatin was first described in the late 1960s. Since then, our knowledge about a superfamily of similar proteins present in mammals, birds, fish, insects, plants and some protozoa has expanded, and their properties as potent peptidase inhibitors have been firmly established.
Magnus, Abrahamson +2 more
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Deleterious effects of plant cystatins against the banana weevil Cosmopolites sordidus [PDF]
Archives of Insect Biochemistry and Physiology, 2010 The general potential of plant cystatins for the development of insect-resistant transgenic plants still remains to be established given the natural ability of several insects to compensate for the loss of active cysteine proteases following inhibitor ...
Christell Van Der Vyver +2 more
exaly +2 more sources
Cystatins S and C in Human Whole Saliva and in Glandular Salivas in Periodontal Health and Disease
Journal of Dental Research, 1994 Cystatins are inhibitors of cysteine proteinases and could play a protective and regulatory role under inflammatory conditions. Since total cystatin activity of whole saliva was increased in periodontal patients (Henskens et al., 1993), we wanted to ...
E C I Veerman +2 more
exaly +2 more sources
Family 2 cystatins inhibit osteoclast-mediated bone resorption in calvarial bone explants
Bone, 2004 Osteoclastic bone resorption depends on the activity of various proteolytic enzymes, in particular those belonging to the group of cysteme protemases. Biochemical studies have shown that cystatins, naturally occurring inhibitors of these enzymes, inhibit
H S Brand, Ulf H Lerner, Anders Grubb
exaly +2 more sources
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2002
Clinical biochemists have long known the analytical and clinical limitations of creatinine and creatinine clearance measurement in the assessment of glomerular filtration rate (GFR). This background is reviewed in the article before assessing the utility of cystatin C, the most promising replacement biochemical marker yet identified.
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Clinical biochemists have long known the analytical and clinical limitations of creatinine and creatinine clearance measurement in the assessment of glomerular filtration rate (GFR). This background is reviewed in the article before assessing the utility of cystatin C, the most promising replacement biochemical marker yet identified.
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The Journal of Biochemistry, 1991
Our recent work on the gene structures for human salivary (S-type) cystatins [Saitoh, E. et al. (1987) Gene 61, 329-338] has suggested that the structures of cystatins which we determined previously at the protein level lack N-terminal peptide portions of the full-sized intact forms. In the present study, attempts were made to isolate full-sized S-type
S, Isemura +3 more
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Our recent work on the gene structures for human salivary (S-type) cystatins [Saitoh, E. et al. (1987) Gene 61, 329-338] has suggested that the structures of cystatins which we determined previously at the protein level lack N-terminal peptide portions of the full-sized intact forms. In the present study, attempts were made to isolate full-sized S-type
S, Isemura +3 more
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Cystatins of Parasitic Organisms
2011The cystatin superfamily comprises several groups of protease inhibitors. In this chapter we will focus on I25 family members, which consist predominantly of the type 2 cystatins. Recently, a wealth of information on these molecules and their activities has been described.
Christian, Klotz +3 more
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Salivary cystatin activity and cystatin C in experimental gingivitis in non‐smokers
Journal of Clinical Periodontology, 2003AbstractBackground: Subjects with natural gingivitis and periodontitis have elevated levels of salivary cystatins compared to periodontally healthy individuals. Experimental gingivitis studies, however, have yielded conflicting results.Aim: The present study investigated whether experimentally induced gingivitis is associated with changes in salivary
van Gils, P.C. +5 more
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Cancer Research, 2004
Abstract The contribution of pericellular proteolysis to tumor progression is well documented. To better understand protease biology and facilitate clinical translation, specific proteolytic systems need to be better defined. In particular, the precise role of endogenous protease inhibitors still needs to be deciphered.
Jun Zhang +11 more
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Abstract The contribution of pericellular proteolysis to tumor progression is well documented. To better understand protease biology and facilitate clinical translation, specific proteolytic systems need to be better defined. In particular, the precise role of endogenous protease inhibitors still needs to be deciphered.
Jun Zhang +11 more
openaire +1 more source
1995
As mentioned in chapter 1, Elzanowski and colleagues were the first to make a real connection between the fetuins, the kininogens and the other members of the cystatin superfamily.1 The idea of a cystatin superfamily was born when it was realized that repeated cystatin-like sequences were present in the kininogens2 and that the stefins were quite ...
Katarzyna M. Dziegielewska +1 more
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As mentioned in chapter 1, Elzanowski and colleagues were the first to make a real connection between the fetuins, the kininogens and the other members of the cystatin superfamily.1 The idea of a cystatin superfamily was born when it was realized that repeated cystatin-like sequences were present in the kininogens2 and that the stefins were quite ...
Katarzyna M. Dziegielewska +1 more
openaire +1 more source