Results 31 to 40 of about 20,732 (256)
Ophthalmology and Therapy, 2019 Introduction Treatment of the anterior segment problems in cystinosis is challenging as oral cysteamine is ineffective in the treatment of corneal problems because of its avascular structure.
Freya Peeters +5 more
doaj +1 more source
Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition. [PDF]
, 2017 The purpose of this study was to use liquid chromatography-mass spectrometry (LC-MS) with XCMS for a quantitative metabolomic analysis of UM1 and UM2 oral cancer cells after knockdown of metabolic enzyme adenylate kinase 2 (AK2) or phosphorylate glycerol
Cheng, Siliangyu +6 more
core +1 more source
Remotely triggered scaffolds for controlled release of pharmaceuticals [PDF]
, 2013 Fe3O4-Au hybrid nanoparticles (HNPs) have shown increasing potential for biomedical applications such as image guided stimuli responsive drug delivery.
Hoskins, Clare +3 more
core +2 more sources
Improved method for the preparation of malonyl coenzyme A
Journal of Lipid Research, 1968 Malonyl coenzyme A is synthesized by transacylating S-malonyl-N-decanoyl cysteamine with coenzyme A. A simplified procedure for the preparation of S-malonyl-N-decanoyl cysteamine, using cysteamine as starting material, is described.
Hans Mohrhauer +4 more
doaj +1 more source
PLoS ONE, 2020 BackgroundEmerging data suggests a possible role for cysteamine as an adjunct treatment for pulmonary exacerbations of cystic fibrosis (CF) that continue to be a major clinical challenge.
Graham Devereux +18 more
doaj +1 more source
Copper-cysteamine and methods of use [PDF]
, 2017 Structure and luminescence properties of a new Cu-Cyteamine (Cu-Cy) crystal material are provided. The crystal structure of the Cu-Cy is determined by single crystal X-ray diffraction.
Chen, Wei, Ma, Lun
core +2 more sources
Myeloperoxidase-oxidase oxidation of cysteamine [PDF]
Biochemical Journal, 1988 Cysteamine oxidation was shown to be catalysed by nanomolar concentrations of myeloperoxidase in a peroxidase-oxidase reaction, i.e. an O2-consuming oxidation of a compound catalysed by peroxidase without H2O2 addition. When auto-oxidation of the thiol was prevented by the metal-ion chelator diethylenetriaminepenta-acetic acid, native, but not heat ...
B E, Svensson, S, Lindvall
openaire +2 more sources
Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages. [PDF]
PLoS ONE, 2017 Members of the Burkholderia cepacia complex are virulent, multi-drug resistant pathogens that survive and replicate intracellularly in patients with cystic fibrosis (CF). We have discovered that B. cenocepacia cannot be cleared from CF macrophages due to
Chandra L Shrestha +8 more
doaj +1 more source
Facile synthesis of cooperative acid-base catalysts by clicking cysteine and cysteamine on an ethylene-bridged periodic mesoporous organosilica [PDF]
, 2016 A periodic mesoporous organosilica (PMO) that contains ethylene bridges was functionalized to obtain a series of cooperative acid-base catalysts. A straightforward, single-step procedure was devised to immobilize cysteine and cysteamine on the support ...
Esquivel Merino, Maria Dolores +6 more
core +2 more sources
Cysteamine ophthalmic hydrogel for the treatment of ocular cystinosis [PDF]
Farmacia Hospitalaria, 2017 Ocular cystinosis is a rare disease characterised by the deposit of cystine crystals on the corneal surface, which hinder patients’ eyesight. Oral cysteamine is given as cysteamine; however, it does not reach the cornea due to the lack of corneal ...
Anxo Fernández-Ferreiro +9 more
doaj +1 more source