Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition. [PDF]
The purpose of this study was to use liquid chromatography-mass spectrometry (LC-MS) with XCMS for a quantitative metabolomic analysis of UM1 and UM2 oral cancer cells after knockdown of metabolic enzyme adenylate kinase 2 (AK2) or phosphorylate glycerol
Cheng, Siliangyu+6 more
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Effect of cysteamine and 13-cis-retinoic acid on bovine in vitro embryo production [PDF]
One of the main factors decreasing the success of an in vitro embryo production is oxidative stress-mediated reactive oxygen species resulting in cellular damages.
Abdolreza RANJBAR+2 more
doaj +1 more source
Controlled Synthesis of Silver Nanoparticles Using Double Reductants and Its Voltammetric Characteristics Study [PDF]
Constructing robust silver nanoparticles (AgNPs) with good shape and dispersibility is of particular interest in analytical applications. Herein, monodispersibility AgNPs with the average size of 20 nm have been successfully prepared via one-pot method ...
Duan, Yubo, Jiang, Xiaochun, Xu, Zhihua
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Cysteamine ophthalmic hydrogel for the treatment of ocular cystinosis [PDF]
Ocular cystinosis is a rare disease characterised by the deposit of cystine crystals on the corneal surface, which hinder patients’ eyesight. Oral cysteamine is given as cysteamine; however, it does not reach the cornea due to the lack of corneal ...
Anxo Fernández-Ferreiro+9 more
doaj +1 more source
X-ray induced photodynamic therapy with copper-cysteamine nanoparticles in mice tumors
Significance Copper-cysteamine nanoparticles can be activated directly by X-rays to produce singlet oxygen. The use of copper-cysteamine nanoparticles (conjugated with pH-low insertion peptide) can enhance the effects of X-ray–induced photodynamic ...
Samana Shrestha+9 more
semanticscholar +1 more source
Low nuclear maturation and fertilization rate is one obstacle in the in vitro embryo production which decrease embryo yield. This problem is presumable related with high production of reactive oxygen species (ROS) during maturation process.
Feni Dwi Kartika Gulo+2 more
doaj +1 more source
Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages. [PDF]
Members of the Burkholderia cepacia complex are virulent, multi-drug resistant pathogens that survive and replicate intracellularly in patients with cystic fibrosis (CF). We have discovered that B. cenocepacia cannot be cleared from CF macrophages due to
Chandra L Shrestha+8 more
doaj +1 more source
Cysteamine inhibits lysosomal oxidation of low density lipoprotein in human macrophages and reduces atherosclerosis in mice [PDF]
Background and aims: We have shown previously that low density lipoprotein (LDL) aggregated by vortexing is internalised by macrophages and oxidised by iron in lysosomes to form the advanced lipid/protein oxidation product ceroid.
Ahmad+73 more
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Evaluation of the effect of adding cysteamine on Ros 308 sperm quality parameters and reduction of lipid peroxidation rate during freezing-thawing process [PDF]
Introduction: Long-term storage of semen is essential for achieving the benefits of artificial insemination (Tuncer et al. 2010). This is carried out by sperm cryopreservation, which stops the sperm metabolic activities, allowing long storage (Bailey et ...
M Nazari , H Daghigh Kia and J Emami
doaj +1 more source
Copper-cysteamine and methods of use [PDF]
Structure and luminescence properties of a new Cu-Cyteamine (Cu-Cy) crystal material are provided. The crystal structure of the Cu-Cy is determined by single crystal X-ray diffraction.
Chen, Wei, Ma, Lun
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