Results 41 to 50 of about 20,732 (256)

Controlled Synthesis of Silver Nanoparticles Using Double Reductants and Its Voltammetric Characteristics Study [PDF]

open access: yes, 2016
Constructing robust silver nanoparticles (AgNPs) with good shape and dispersibility is of particular interest in analytical applications. Herein, monodispersibility AgNPs with the average size of 20 nm have been successfully prepared via one-pot method ...
Duan, Yubo, Jiang, Xiaochun, Xu, Zhihua
core   +2 more sources

Spectroscopic Investigation of Cysteamine Dioxygenase

open access: yesBiochemistry, 2020
Thiol dioxygenases are mononuclear non-heme FeII-dependent metalloenzymes that initiate the oxidative catabolism of thiol-containing substrates to their respective sulfinates. Cysteine dioxygenase (CDO), the best characterized mammalian thiol dioxygenase, contains a three-histidine (3-His) coordination environment rather than the 2-His-1-carboxylate ...
Rebeca L. Fernandez   +4 more
openaire   +3 more sources

Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication

open access: yesNeurobiology of Disease, 2020
A number of publications have reported that cysteamine has significant therapeutic effects on several aspects of Parkinson's disease (PD)-related pathology but none of these studies have evaluated its impact on pathological forms of α-Synuclein (α-Syn ...
Alberto Siddu   +7 more
doaj   +1 more source

Synthesis of diacylated γ-glutamyl-cysteamine prodrugs, and in vitro evaluation of their cytotoxicity and intracellular delivery of cysteamine [PDF]

open access: yes, 2015
To overcome the major disadvantages of cysteamine, the only registered treatment for the rare genetic disease cystinosis, nine prodrugs of γ-glutamyl-cysteamine (4) were synthesized for evaluation.
Anderson, Rosaleen   +5 more
core   +1 more source

A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan

open access: yesJournal of Chemistry, 2013
A carbon-paste electrode modified with ferrocenecarboxaldehyde and NiO nanoparticle (NiO/NPs) was used for the sensitive and selective voltammetric determination of cysteamine in the presence of tryptophan.
Hassan Karimi-Maleh   +4 more
doaj   +1 more source

Cysteamine in Maturation Medium Enhances Nuclear Maturation and Fertilization Rate of Sheep Oocytes In Vitro

open access: yesHayati Journal of Biosciences, 2020
Low nuclear maturation and fertilization rate is one obstacle in the in vitro embryo production which decrease embryo yield. This problem is presumable related with high production of reactive oxygen species (ROS) during maturation process.
Feni Dwi Kartika Gulo   +2 more
doaj   +1 more source

A monoclinic polymorph of cysteamine hydrochloride [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2009
cloruro de 2-mercaptoetano-aminio), C(2)H(8)NS(+)·Cl(-), la sal de hidrocloruro de cisteamina, en contraste con el polimorfo triclínico previamente informado [Kim et al. (2002▶). Polyhedron, 21, 225-228], cristalizado en el sistema cristalino monoclínico.
Saeed Ahmad   +2 more
openaire   +3 more sources

Scalable Access to N‑Acylindole Linkages: Enabling the Synthesis of Antitrypanosomal Noncanonical Cyclic Peptides for Chagas Disease

open access: yesAngewandte Chemie, EarlyView.
A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley   +2 more sources

Synthesis Of Some Novel Silver-Cysteamine Complexes

open access: yesMolecules, 2000
The aim of this research was to synthesize some new silver-cysteamine complexes of potential biological interest. Reactions were carried out between silver nitrate and cysteamine (2-aminoethanethiol hydrochloride) under different conditions of pH and ...
Davood Nematollahi   +2 more
doaj   +1 more source

Limitations and Challenges in the Stability of Cysteamine Eye Drop Compounded Formulations

open access: yesPharmaceuticals, 2021
Accumulation of cystine crystals in the cornea of patients suffering from cystinosis is considered pathognomonic and can lead to severe ocular complications.
Cristina Martín-Sabroso   +7 more
doaj   +1 more source

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