Results 1 to 10 of about 747,792 (297)

Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.

Cell Metabolism, 2019
Cysteine acts both as a building unit for protein translation and as the limiting substrate for glutathione synthesis to support the cellular antioxidant system.
Jiajun Zhu, M. Berisa, Simon Schwörer, Weige Qin, J. Cross, C. Thompson   +5 more
semanticscholar   +1 more source

Burning fat with cysteine depletion

Cell Stress
Removing certain essential amino acids from the diet is known to promote weight loss in rodents via effects on food intake and energy expenditure. Two complementary articles by Varghese et al [Nature 643(8072)] and Lee et al [Nature Metabolism 7(6)] now ...
Brittney Adams, Stanislaw Walkowiak, Mohammed K Hankir   +2 more
doaj   +1 more source

Conversion of Methionine to Cysteine in Lactobacillus paracasei Depends on the Highly Mobile cysK-ctl-cysE Gene Cluster

Frontiers in Microbiology, 2018
Milk and dairy products are rich in nutrients and are therefore habitats for various microbiomes. However, the composition of nutrients can be quite diverse, in particular among the sulfur containing amino acids.
Daniel Wüthrich, Stefan Irmler, Hélène Berthoud, Barbara Guggenbühl, Elisabeth Eugster, Rémy Bruggmann   +5 more
doaj   +1 more source

Indirect Routes to Aminoacyl-tRNA: The Diversity of Prokaryotic Cysteine Encoding Systems

Frontiers in Genetics, 2022
Universally present aminoacyl-tRNA synthetases (aaRSs) stringently recognize their cognate tRNAs and acylate them with one of the proteinogenic amino acids.
Takahito Mukai, Takahito Mukai, Kazuaki Amikura, Xian Fu, Dieter Söll, Dieter Söll, Ana Crnković, Ana Crnković   +7 more
doaj   +1 more source

Multi-objective optimization of methionine+cysteine levels in diets for growing pigs

Revista Colombiana de Ciencias Pecuarias, 2020
Background: The addition of synthetic methionine to growing pig diets should consider the requirements of the methionine+cysteine complex, as most cysteine is obtained through dietary methionine.
José L. Figueroa-Velasco, José A. Martínez-Aispuro, María T. Sánchez-Torres, Humberto Vaquera-Huerta, José L. Cordero-Mora, Rafael Nieto-Aquino   +5 more
doaj   +1 more source

Catch, Modify and Analyze: Methods of Chemoselective Modification of Cysteine-Containing Peptides

Molecules, 2022
One effective solution in the analysis of complex mixtures, including protein or cell hydrolysates, is based on chemoselective derivatization of a selected group of compounds by using selective tags to facilitate detection. Another method is based on the
Marta Kowalska, Remigiusz Bąchor
doaj   +1 more source

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

Nature Communications, 2017
Cysteine hydropersulfide (CysSSH) occurs in abundant quantities in various organisms, yet little is known about its biosynthesis and physiological functions.
T. Akaike, T. Ida, Fan-Yan Wei, M. Nishida, Y. Kumagai, M. Alam, H. Ihara, T. Sawa, Tetsuro Matsunaga, S. Kasamatsu, Akiyuki Nishimura, Masanobu Morita, K. Tomizawa, A. Nishimura, Satoshi Watanabe, K. Inaba, H. Shima, N. Tanuma, Minkyung Jung, Shigemoto Fujii, Yasuo Watanabe, M. Ohmuraya, P. Nagy, M. Feelisch, J. Fukuto, H. Motohashi   +25 more
semanticscholar   +1 more source

Possible Reaction Mechanisms Involved in Degradation of Patulin by Heat-Assisted Cysteine under Highly Acidic Conditions

Toxins, 2022
Patulin (PAT) is one of mycotoxins that usually contaminates apple juice, and it is not easily detoxified by cysteine (CYS) at room temperature due to the highly acidic conditions based on the Michael addition reaction.
Enjie Diao, Kun Ma, Minghua Li, Hui Zhang, Peng Xie, Shiquan Qian, Huwei Song, Ruifeng Mao, Liming Zhang   +8 more
doaj   +1 more source

Chemical and Biological Mechanisms Relevant to the Rescue of MG-132-Treated Neurons by Cysteine

Antioxidants
Proteasome dysfunctions are observed in many human pathologies. To study their role and potential treatment strategies, models of proteasome inhibition are widely used in biomedical research.
Anna-Katharina Ückert, Ilinca Suciu, Anja Land, Anna-Sophie Spreng, Hannah Welte, Doreen Herzog, Michael Basler, Marcel Leist   +7 more
doaj   +1 more source

Transcriptomic analysis reveals the functions of H2S as a gasotransmitter independently of Cys in Arabidopsis

Frontiers in Plant Science, 2023
Numerous studies have revealed the gasotransmitter functions of hydrogen sulfide (H2S) in various biological processes. However, the involvement of H2S in sulfur metabolism and/or Cys synthesis makes its role as a signaling molecule ambiguous.
Huihui Fang, Zhenyuan Yu, Kehong Xing, Lingyi Zhou, Yuke Shao, Xiaofang Zhang, Yanxi Pei, Lu Zhang   +7 more
doaj   +1 more source