Results 1 to 10 of about 589,705 (297)
Evaluation of flour protein for different bread wheat genotypes [PDF]
Six different bread wheat genotypes; two Egyptian commercial varieties (control); Giza-168 and Gemmeiza-11, and four promising lines; L84 and L148, resulted via hybridization and M10 and M34 via radiation mutation program) were rheologically evaluated ...
M. A. Abdelaleem, K. F. Al-Azab
doaj +1 more source
50 shades of oxidative stress: A state-specific cysteine redox pattern hypothesis
Oxidative stress is biochemically complex. Like primary colours, specific reactive oxygen species (ROS) and antioxidant inputs can be mixed to create unique “shades” of oxidative stress.
James N. Cobley
doaj +1 more source
Roles of sulfur-containing amino acids in gastrointestinal physiology and pathophysiology [PDF]
nema
Todorović Dušan D. +8 more
doaj +1 more source
Cells employ post-translational modifications (PTMs) as key mechanisms to expand proteome diversity beyond the inherent limitations of a concise genome.
Ivy Guan +7 more
doaj +1 more source
Biomimetic Ketone Reduction by Disulfide Radical Anion
The conversion of ribonucleosides to 2′-deoxyribonucleosides is catalyzed by ribonucleoside reductase enzymes in nature. One of the key steps in this complex radical mechanism is the reduction of the 3′-ketodeoxynucleotide by a pair of cysteine residues,
Sebastian Barata-Vallejo +5 more
doaj +1 more source
A strategy to improve the cancer therapies involves agents that cause the depletion of the endogenous antioxidant glutathione (GSH), increasing its efflux out of cells and inducing apoptosis in tumoral cells due to the presence of reactive oxygen species.
Lillian G. Ramírez-Palma +6 more
doaj +1 more source
Bacterial Cysteine-Inducible Cysteine Resistance Systems [PDF]
ABSTRACT Cysteine donates sulfur to macromolecules and occurs naturally in many proteins. Because low concentrations of cysteine are cytotoxic, its intracellular concentration is stringently controlled. In bacteria, cysteine biosynthesis is regulated by feedback inhibition of the activities of serine acetyltransferase (SAT) and 3-
Kazuhiro, Takumi, Gen, Nonaka
openaire +2 more sources
Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington’s Disease
Huntington’s disease (HD) is caused by expansion of polyglutamine repeats in the protein huntingtin, which affects the corpus striatum of the brain. The polyglutamine repeats in mutant huntingtin cause its aggregation and elicit toxicity by affecting ...
Bindu D. Paul
doaj +1 more source
Mechanistic Insight into SARS-CoV-2 Mpro Inhibition by Organoselenides: The Ebselen Case Study
The main protease (Mpro) of SARS-CoV-2 is a current target for the inhibition of viral replication. Through a combined Docking and Density Functional Theory (DFT) approach, we investigated in-silico the molecular mechanism by which ebselen (IUPAC: 2 ...
Andrea Madabeni +4 more
doaj +1 more source
The bactericidal effects of fluorescent metal nanoclusters have impeded their bacterial bioimaging applications due to the reactive oxygen species (ROS) generation that is induced by the nanoclusters in bacteria to cause bacterial death.
Dyah Ika Krisnawati +9 more
doaj +1 more source

