Protein Redox State Monitoring Studies of Thiol Reactivity
Protein cysteine thiol status is a major determinant of oxidative stress and oxidant signaling. The -SulfoBiotics- Protein Redox State Monitoring Kit provides a unique opportunity to investigate protein thiol states.
Yuichiro J. Suzuki +5 more
doaj +1 more source
Development of Lactococcus lactis Biosensors for Detection of Sulfur-Containing Amino Acids
The sulfur-containing amino acids methionine and cysteine play an important role in food industry. These amino acids are used to confer a sulfur smell or meat-related aroma to food products.
Jhonatan A. Hernandez-Valdes +3 more
doaj +1 more source
Detecting peroxiredoxin hyperoxidation by one-dimensional isoelectric focusing [PDF]
The activity of typical 2-cys peroxiredoxin (Prxs) can be regulated by hyperoxidation with a consequent loss of redox activity. Here we developed a simple assay to monitor the level of hyperoxidation of different typical 2-cys prxs simultaneously.
Bulleid, Neil J., Cao, Zhenbo
core +1 more source
Oxidation Resistance of the Sulfur Amino Acids: Methionine and Cysteine
Sulfur amino acids are a kind of amino acids which contain sulfhydryl, and they play a crucial role in protein structure, metabolism, immunity, and oxidation.
Peng Bin, Ruilin Huang, Xihong Zhou
semanticscholar +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Effect of Potassium and Sulfur Fertilization on Seed Quality of Faba Bean (Vicia faba L.)
Faba bean seeds are regarded as a highly valuable protein source for human and animal nutrition. High yield and quality of faba bean require adequate mineral nutrition.
Przemysław Barłóg +2 more
doaj +1 more source
Endothelial cell apoptosis is an important pathophysiology in many cardiovascular diseases. The gasotransmitter nitric oxide (NO) is known to regulate cell survival and apoptosis. However, the mechanism underlying the effect of NO remains unclear.
Hanlin Peng +8 more
doaj +1 more source
Comparing the effect of using normal saline, N-acetyl cysteine and not using them in endotracheal tube suction on physiologic parameters and the amount of secretions in intubated patients under mechanical ventilation [PDF]
Aims: Today a large number of patients hospitalized in Intensive Care Unit need mechanical ventilation via an artificial air way. Since these patients have endotracheal tube, endotracheal suctioning is necessary for increasing oxygenation, cleaning the ...
Akbaryan Deheki, N. +6 more
core
Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological Targets
Proteolytic enzymes are crucial for a variety of biological processes in organisms ranging from lower (virus, bacteria, and parasite) to the higher organisms (mammals).
S. Verma, R. Dixit, K. Pandey
semanticscholar +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source

